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. 2025 May 7;16:1466188. doi: 10.3389/fneur.2025.1466188

Table 2.

Baseline characteristics of patients undergoing neurosurgical clipping.

Variables Total (n = 324) Good functional outcome (n = 218) Poor functional outcome (n = 106) p-value
Age, years 60.0 (51.75–68.00) 58.5 (51.00–67.00) 63.0 (53.25–69.00) 0.020
Gender 0.720
Female 208 (64.2%) 138 (63.3%) 70 (66.0%)
Male 116 (35.8%) 80 (36.7%) 36 (34.0%)
Hunt–Hess grade <0.001
0–3 200 (61.7%) 167 (76.6%) 33 (31.1.2%)
4–5 124 (38.3%) 51 (23.4%) 73 (68.9%)
Hypertension 1.000
No 91 (28.1%) 61 (28.0%) 30 (28.3%)
Yes 233 (71.9%) 157 (72.0%) 76 (71.7%)
Diabetes mellitus 1.000
No 308 (95.1%) 207 (95.0%) 101 (95.3%)
Yes 16 (4.9%) 11 (5.0%) 5 (4.7%)
Body temperature, °C 36.80 (36.5–37.0) 36.80 (36.5–37.0) 36.80 (36.5–37.1) 0.975
MAP, mmHg 111.00 (98.67–122.00) 111.00 (98.75–123.00) 111.50 (97.75–120.67) 0.741
GCS score <0.001
3–8 95 (29.3%) 34 (15.6%) 61 (57.5%)
9–12 23 (7.1%) 17 (7.8%) 6 (5.7%)
12–15 206 (63.6%) 167 (76.6%) 39 (36.8%)
mFS <0.001
0–2 136 (42.0%) 121 (55.5%) 15 (14.2%)
3–4 188 (58.0%) 97 (44.5%) 91 (85.8%)
Length, mm 4.00 (3.00–6.00) 4.00 (3.00–5.20) 4.00 (3.00–6.00) 0.651
Width, mm 4.00 (3.00–5.00) 4.00 (3.00–5.00) 4.00 (3.00–5.00) 0.088
Height, mm 4.00 (3.00–5.00) 4.00 (3.00–5.00) 4.00 (3.00–5.00) 0.093
Aneurysm volume, mm3 33.51 (14.14–65.45) 31.42 (14.14–62.83) 33.51 (14.14–89.54) 0.186
Aneurysm location 0.231
Anterior cerebral artery 106 (32.7%) 75 (34.4%) 31 (29.2%)
Middle cerebral artery 126 (38.9%) 81 (37.2%) 45 (42.5%)
Internal carotid artery 40 (12.3%) 26 (11.9%) 14 (13.2%)
Posterior communicating artery 44 (13.6%) 33 (15.1%) 11 (10.4%)
Posterior circulation 8 (2.5%) 3 (1.4%) 5 (4.7%)
Presence of hematoma 0.791
No 276 (85.2%) 187 (85.8%) 89 (84.0%)
Yes 48 (14.8%) 31 (14.2%) 17 (16.0%)
D-dimer, mg/L 1.64 (0.73–2.93) 1.33 (0.66–2.48) 2.33 (1.34–3.99) <0.001
PLT, ×109/L 260.00 (160.75–349.25) 286.00 (192.75–362.50) 194.50 (119.25–291.75) <0.001

MAP, mean arterial pressure; GCS, Glasgow Coma Scale; PLT, platelet.