Table 3.
Comparison of clinical and imaging parameters between amblyopic, fellow and control eyes in myopic group
| Parameter, mean ± standard deviation | Hyperopic Group | |||||
|---|---|---|---|---|---|---|
| Amblyopic Eyes | Fellow Eyes | Control Eyes | p1 value (Amblyopic vs. Fellow) | P2 value (Amblyopic vs. Control) | P3 value (Fellow vs. Control) | |
| Best corrected visual acuity, logMAR | 0.45 ± 0.31 | 0.02 ± 0.04 | 0.02 ± 0.03 | <0.001 a | <0.001 b | 0.642c |
| Spherical equivalent, diopters | +4.07 ± 2.03 | +1.44 ± 1.66 | +1.20 ± 0.80 | <0.001 a | <0.001 b | 0.815c |
| Axial length, mm | 22.05 ± 0.94 | 22.76 ± 0.75 | 22.57 ± 0.68 | <0.001 d | 0.004 c | 0.734c |
| Central macular thickness, μm | 222.83 ± 14.66 | 221.73 ± 14.87 | 222.18 ± 14.45 | 0.544a | 0.654b | 0.758b |
| Subfoveal choroidal thickness, μm | 363.80 ± 106.95 | 337.23 ± 105.99 | 334.04 ± 101.84 | 0.077d | 0.068c | 0.689c |
| Choroidal area | ||||||
| Total, μm2 | 1717601.94 ± 528402.53 | 1537688.87 ± 490917.43 | 1567899.98 ± 490917.43 | 0.084d | 0.090c | 0.792c |
| Luminal, μm2 | 1067082.44 ± 265282.33 | 984534.77 ± 276684.07 | 1005548.77 ± 276684.07 | 0.035 d | 0.048 c | 0.713c |
| Stromal, μm2 | 650519.50 ± 271149.078 | 553154.10 ± 224281.84 | 562351.21 ± 224281.84 | 0.060d | 0.059c | 0.674c |
| Choroidal vascular index, % | 63.46 ± 5.61 | 64.85 ± 4.21 | 64.14± 4.32 | 0.082a | 0.092b | 0.801c |
| Choriocapillaris vascular density, % | ||||||
| Macular | ||||||
| Superior parafoveal | 51.27 ± 3.13 | 52.64 ± 3.20 | 52.76 ± 3.14 | 0.098a | 0.104b | 0.612c |
| Temporal parafoveal | 52.20 ± 5.25 | 53.16 ± 3.30 | 52.96 ± 3.20 | 0.344a | 0.287b | 0.743b |
| Inferior parafoveal | 52.88 ± 3.58 | 53.28 ± 2.65 | 53.26 ± 2.98 | 0.610d | 0.589c | 0.682c |
| Nasal parafoveal | 52.17 ± 3.00 | 51.93 ± 4.16 | 51.12 ± 3.46 | 0.773a | 0.658b | 0.771c |
| Foveal | 48.15 ± 12.19 | 49.06 ± 12.35 | 49.24 ± 12.50 | 0.504a | 0.420b | 0.548b |
| Peripapillary | ||||||
| Superior peripapillary | 55.48 ± 7.50 | 56.11 ± 4.73 | 57.01 ± 5.89 | 0.703d | 0.432c | 0.789c |
| Temporal peripapillary | 61.96 ± 10.14 | 61.90 ± 9.65 | 62.10 ± 9.85 | 0.974a | 0.785b | 0.801b |
| Inferior peripapillary | 51.80 ± 9.16 | 52.27 ± 9.09 | 52.19 ± 9.12 | 0.007 d | 0.023 c | 0.675c |
| Nasal peripapillary | 66.37 ± 7.01 | 62.32 ± 8.98 | 63.42 ± 8.90 | 0.007 a | 0.014 b | 0.702c |
a Wilcoxon signed rank test
b Mann-Whitney U test
c Independent samples t-test
d Paired samples t-test