Table 3.
Results from linear regression analyses of PGSs in the diagnostic groups, compared with people with no psychiatric disorder
| Outcome diagnosis | Schizophrenia PGS | Sleep duration PGS | Insomnia PGS | Eveningness PGS | Long sleep duration PGS | Short sleep duration PGS | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Full Finngen sample | OR | CI | p | OR | CI | p | OR | CI | p | OR | CI | p | OR | CI | p | OR | CI | p |
| Schizophrenia (N = 6,280) | 2.39 | 2.32–2.46 | < 2 × 10−16 | 1.09 | 1.06–1.11 | 1 × 10−10 | 1.00 | 0.97–1.02 | .698 | 1.06 | 1.04–1.09 | 2 × 10−6 | 1.09 | 1.06–1.12 | 2 × 10−11 | 0.96 | 0.94–0.98 | .002 |
| Affective psychotic and bipolar disorders (N = 9,563) | 1.64 | 1.60–1.67 | < 2 × 10−16 | 1.02 | 1.00–1.05 | .026 | 1.08 | 1.05–1.10 | 3 × 10−12 | 1.01 | 0.99–1.03 | .319 | 1.12 | 1.09–1.14 | < 2 × 10−16 | 1.05 | 1.03–1.07 | 1 × 10−5 |