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. 2025 May 8;12:1459761. doi: 10.3389/fmolb.2025.1459761

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Copyright © 2025 Romani, Melloni, Lodi, Bompan, Foschi, Zauli, Pozza, Secchiero, Zauli, Previati and Voltan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representation of the most common retinal tumors in adults: intraocular lymphoma and gliomas. Primary vitreoretinal lymphoma (PVRL) is a rare type of central nervous system lymphoma (PCNSL) that affects the retina, vitreous and in some cases also the optic nerve. Glioma is a rare central nervous system tumor that affects the retina and optic nerve. The image reports miRNAs localized in the vitreous humor that may play a role in PVRL. In the zoomed panel it is reported a schematic structure of the outer layer of the retina with interaction between photoreceptors and retinal pigmented epithelial (RPE) cells. Created with BioRender.