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. 2025 Mar 6;60(6):715–726. doi: 10.1007/s00535-025-02231-1

Table 2.

Pouch outcomes and endoscopic phenotypes

Characteristic N1
Pouch outcomes
 Chronic pouchitis 390 125 (32%)
 Acute pouchitis 377 115 (31%)
 Diverting loop ileostomy 389 19 (4.9%)
 Pouch excision 387 3 (0.8%)
 Pouch failure 389 19 (4.9%)
Phenotypes at the initial postoperative scope
 Normal 392 80 (20%)
 Afferent limb involvement 280 57 (20%)
 Inlet involvement 325 112 (34%)
 Diffuse inflammation of the pouch body 390 63 (16%)
 Focal inflammation of the pouch body 390 230 (59%)
 Cuffitis 250 125 (50%)
 Pouch-related fistula 392 4 (1.0%)
 Number of inflammatory phenotypes at the first scope 392
 0 80 (20%)
 1 122 (31%)
 2–3 168 (43%)
 4–5 22 (5.6%)
Phenotypes at 3 years after ileostomy takedown
 Normal (3yrs) 258 55 (21%)
 Afferent limb involvement (3yrs) 174 38 (22%)
 Inlet involvement (3yrs) 204 70 (34%)
 Diffuse inflammation of the pouch body (3yrs) 258 49 (19%)
 Focal inflammation of the pouch body (3yrs) 258 143 (55%)
 Cuffitis (3yrs) 177 96 (54%)
 Pouch-related fistula (3yrs) 256 7 (2.7%)
 Number of inflammatory phenotypes at 3yrs 258
 0 55 (21%)
 1 73 (28%)
 2–3 109 (42%)
 4–5 21 (8.1%)
Phenotypes at 10 years after ileostomy takedown
 Normal (10yrs) 99 12 (12%)
 Afferent limb involvement (10yrs) 70 18 (26%)
 Inlet involvement (10yrs) 75 37 (49%)
 Diffuse inflammation of the pouch body (10yrs) 99 11 (11%)
 Focal inflammation of the pouch body (10yrs) 99 75 (76%)
 Cuffitis (10yrs) 83 48 (58%)
 Pouch-related fistula (10yrs) 99 6 (6.1%)
 Number of inflammatory phenotypes at 10yrs 99
 0 12 (12%)
 1 16 (16%)
 2–3 61 (62%)
 4–5 10 (10%)
Overall phenotypes determined by all scopes
 Normal (Overall) 392 57 (15%)
 Afferent limb involvement (Overall) 336 88 (26%)
 Inlet involvement (Overall) 363 168 (46%)
 Diffuse inflammation of the pouch body (Overall) 390 106 (27%)
 Focal inflammation of the pouch body (Overall) 390 216 (55%)
 Cuffitis (Overall) 265 155 (58%)
 Pouch-related fistula (Overall) 392 19 (4.8%)
 Number of overall inflammatory phenotypes 392
 0 57 (15%)
 1 95 (24%)
 2–3 188 (48%)
 4–5 52 (13%)

 1n (%)