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. 2025 Mar 6;60(6):715–726. doi: 10.1007/s00535-025-02231-1

Table 3.

Cox proportional hazards model to assess factors predicting pouch outcomes

Characteristic HR1 95% CI1 P-value*
Chronic pouchitis
 Age at colectomy (yrs) 0.96506 0.94463, 0.98593 0.00112
 Anastomosis type
1. Staple – –
2. Hand-sewn 0.55299 0.31227, 0.97927 0.04217
 Focal inflammation of the pouch body at the initial postoperative scope 2.15214 1.06298, 4.35727 0.03320
 Preoperative azathioprine/6-mercaptopurine 1.28913 0.75895, 2.18966 0.34744
 Dysplasia/Colorectal Cancer 0.96549 0.34947, 2.66741 0.94600
 Disease duration until surgery (yrs) 1.00014 0.95737, 1.04482 0.99504
Pouch failure
 Age at colectomy (yrs) 0.92806 0.86834, 0.99190 0.02783
 No postoperative complications 0.59421 0.13932, 2.53438 0.48183
 Preoperative tumor necrosis factor inhibitors 4.55330 1.07511, 19.2841 0.03956
 Inlet involvement at the initial postoperative scope 6.31348 1.29217, 30.8474 0.02281

1HR   Hazard Ratio, CI Confidence Interval

*The bold values indicate p-value < 0.05