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. 2025 Mar 6;60(6):715–726. doi: 10.1007/s00535-025-02231-1

Table 5.

Clinical subscore of pouchitis disease activity index and endoscopic phenotypes

Symptoms
Variable N Clinical subscore (0), N = 2711

Clinical subscore

(1–3), N = 3391

Clinical subscore (4–6), N = 621 P-value2
Normal 672 70 (26%) 54 (16%) 2 (3.2%)  < 0.001
Afferent limb involvement 465 16 (10%) 55 (22%) 22 (43%)  < 0.001
Inlet involvement 538 42 (23%) 114 (39%) 45 (75%)  < 0.001
Diffuse involvement of the pouch body 669 19 (7.0%) 67 (20%) 34 (55%)  < 0.001
Focal involvement of the pouch body 669 172 (63%) 201 (60%) 25 (40%) 0.004
Cuffitis 466 128 (55%) 110 (53%) 20 (71%) 0.20
Pouch-related fistula 668 7 (2.6%) 11 (3.3%) 2 (3.2%) 0.84
Number of inflammatory phenotypes 672  < 0.001
Normal or single phenotype 129 (48%) 163 (48%) 11 (18%)
Multiple phenotype 142 (52%) 176 (52%) 51 (82%)

1n (%)

2Fisher's exact test, the bold values indicate P-value < 0.05