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. 2025 May 22;15:17723. doi: 10.1038/s41598-025-01233-6

Table 3.

Cost (mean and SD) in CAD dollar by characteristics of patients.

Characteristic Healthcare costs (n = 1372) Productivity costs (n = 928)
n Mean (SD) P-valuea n Mean (SD) P-valuea
Sociodemographic factors
Age < 0.001 0.004
16–34 582 12,566 (41,043) 431 3,634 (7,638)
35–64 589 22,312 (54,244) 497 5,045 (8,349)
≥ 65 201 29,833 (58,038) - -
Sex 0.048 < 0.001
Male 736 20,876 (47,109) 546 3,659 (7,575)
Female 636 17,432 (53,262) 382 5,433 (8,594)
Employment status < 0.001
Employed 915 16,623 (45,370) - -
School 147 10,345 (38,586) - -
Retired 188 28,065 (59,696) - -
Others 90 35,305 (73,165) - -
Living situation 0.025 0.509
Alone 334 23,704 (47,979) 195 4,924 (8,505)
With others 1031 17,824 (50,805) 730 4,265 (7,940)
Education level < 0.001 0.005
Less than high school 89 38,126 (58,601) 34 4,266 (7,719)
High school and vocational 528 22,545 (56,707) 336 3,927 (8,330)
University 751 14,771 (42,983) 556 4,691 (7,913)
Ethnicity < 0.001 0.130
Caucasian 706 24,092 (55,363) 458 4,868 (8,347)
Asian 328 10,832 (30,442) 223 3,649 (6,114)
Others 335 17,549 (52,801) 243 4,189 (9,004)
Years lived in Canada < 0.001 0.050
> 10 years 1176 20,988 (53,237) 803 4,605 (8,323)
≤ 10 years 193 9,074 (20,707) 122 3,077 (5,936)
Psychological and medical factors
Somatic symptoms severity (PHQ-15) 0.299 0.540
< 15 1310 18,616 (49,839) 890 4,431 (8,138)
≥ 15 27 47,634 (116,766) 13 5,116 (7,222)
Pain catastrophizing 0.598 0.578
< 30 1280 17,964 (46,511) 880 4,362 (8,025)
≥ 30 61 38,910 (93,221) 33 5,900 (9,352)
Psychological distress (PHQ-4) 0.081 0.021
< 9 1335 18,757 (48,880) 911 4,266 (7,475)
≥ 9 35 32,494 (73,160) 16 10,209 (23,591)
Health-related quality of life (SF-12) 0.020 < 0.001
< 100 272 28,054 (61,106) 142 8,352 (12,349)
≥ 100 1087 16,678 (45,854) 779 3,659 (6,754)
Pre-injury comorbidities number < 0.001 < 0.001
0 635 13,091 (34,819) 506 3,424 (6,474)
1 409 19,072 (52,688) 283 4,870 (9,898)
≥ 2 328 31,520 (66,862) 139 6,925 (8,468)
Trauma-related factors 
ED visited < 0.001 0.786
VGH (Vancouver) 1120 18,548 (50,891) 765 4,129 (7,399)
RCH (New Westminster) 212 24,829 (49,516) 137 5,372 (10,316)
KGH (Kelowna) 40 10,362 (16,655) 26 6,879 (11,794)
Crash time (Season) < 0.001 0.552
Spring 241 20,884 (59,154) 168 4,550 (9,705)
Summer 258 24,056 (52,462) 169 5,165 (9,164)
Fall 444 19,220 (52,865) 302 4,151 (7,290)
Winter 429 15,588 (38,640) 289 4,092 (7,006)
Road user type 0.001 0.863
Driver 629 16,363 (46,285) 455 4,497 (9,091)
Passenger 203 18,810 (52,679) 125 4,199 (6,821)
Motorcyclist 108 24,163 (47,771) 93 5,150 (8,820)
Pedestrian 265 27,369 (60,460) 132 3,931 (6,079)
Cyclist 167 14,840 (42,000) 123 4,102 (6,227)
ISS < 0.001 0.012
≤ 3 770 5,952 (14,378) 554 3,644 (6,492)
4–8 220 7,679 (15,424) 151 4,604 (9,818)
9–15 193 28,432 (38,607) 109 6,499 (11,284)
≥ 16 188 78,148 (106,096) 113 5,764 (8,087)
GCS < 0.001 0.426
3–8 22 134,714 (85,053) 14 2,905 (3,343)
9–13 23 113,279 (150,742) 17 1,441 (2,411)
≥ 14 1233 16,267 (42,087) 820 4,566 (8,288)
Head injury 0.020 0.374
Yes 521 22,678 (60,784) 349 4,791 (8,334)
No 851 17,199 (42,088) 579 4,148 (7,877)
Neck injury < 0.001 0.503
Yes 517 12,469 (36,118) 370 4,729 (8,014)
No 855 23,394 (56,478) 558 4,164 (8,087)
Torso injury < 0.001 0.325
Yes 534 31,416 (68,046) 335 4,827 (7,932)
No 838 11,546 (31,678) 593 4,142 (8,117)
Spine/back injury 0.004 0.064
Yes 471 22,564 (64,396) 326 5,133 (8,783)
No 901 17,563 (40,549) 602 3,987 (7,605)
Upper extremity injury 0.173 0.005
Yes 699 19,824 (53,985) 475 5,091 (9,264)
No 673 18,714 (45,674) 453 3,654 (6,477)
Lower extremity injury < 0.001 0.510
Yes 664 24,497 (60,185) 448 4,532 (7,830)
No 708 14,387 (37,610) 480 4,256 (8,262)

SD: standard deviation; PHQ-15: Patient Health Questionnaire-15; PHQ-4: Patient Health Questionnaire-4; SF-12: Short Form 12 survey; VGH: Vancouver General Hospital; RCH: Royal Columbian Hospital; KGH: Kelowna General Hospital; ED: emergency department; ISS: injury severity score; GCS: Glasgow Coma Scale. a univariate model.