Table 3.

Efficacy of serum CTH, IL-6, CRP, IL-10, AFP, and the combination of CTH + AFP in diagnosing HCC.

Parameter	AUC	95% confidence interval	Critical value	Sensitivity%	Specificity%	P-value
CTH	0.83	0.79–0.87	12.55	64.6	83.3	< 0.0001
IL-6	0.77	0.72–0.81	123.95	77.2	65.0	< 0.0001
CRP	0.78	0.73–0.82	11.95	68.5	79.8	< 0.0001
IL-10	0.76	0.72–0.81	106.3	60.6	81.7	< 0.0001
AFP	0.82	0.77–0.86	5.85	70.9	82.2	< 0.0001
CTH + AFP	0.88	0.84–0.91	NA	73.2	85.2	< 0.0001

AFP alpha-fetoprotein; AUC area under the curve; CRP C-reactive protein; CTH cystathionine γ-lyase; IL interleukin.