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. 2025 May 1;45:e00472. doi: 10.1016/j.plabm.2025.e00472

Table 3.

The table compares the biotin tolerance levels of the old and new reagents measured in our lab with the biotin tolerance levels indicated in the package inserts. The biotin tolerance levels were determined as the final biotin concentrations that resulted in a ±10 % change.


Biotin tolerance of old reagents
Biotin tolerance of new reagents
Reagents Determined by our laboratory (ng/mL) Package inserts (ng/mL) Determined by our laboratory (ng/mL) Package inserts (ng/mL)
FT4 <200 ≤100 >1500 ≤1200
ATG <50 <60 <1250 ≤1200
TG <50 <30 >1500 ≤1200
AFP <400 <180 >1500 ≤1200