Table 6.
The table lists the biotin tolerance levels of onboard reagents compared with the specifications in the package inserts. The biotin tolerance levels were determined as the final biotin levels that fell within a ±10 % change. For the reagents CEA, CA125, CA153, CA199, and HBeAg, no final data point fell within the ±10 % change threshold, and thus they are classified as "Indeterminate."
| Biotin tolerance of onboard reagents | ||
|---|---|---|
| Reagents | Determined by our laboratory (ng/mL) | Package inserts (ng/mL) |
| TSH (newer) | <1500 | ≤1200 |
| CEA (older) | Indeterminate | <120 |
| CA125 (older) | Indeterminate | <70 |
| CA153 (older) | Indeterminate | <100 |
| CA199 (older) | Indeterminate | <100 |
| FPSA (newer) | <1500 | <1200 |
| TPSA (newer) | <2500 | <1200 |
| HBeAg (older) | Indeterminate | <40 |
| HBsAg (newer) | <500 | ≤1200 |