Table 1. CYP125MRCA dissociation (Kd) constants (μM) for various steroid substrates using the Hill modela.
| Substrate | K d (μM) (n*) |
|---|---|
| Cholest-4-en-3-one | 0.85 ± 0.02 (2.15) |
| Cholesterol | 2.00 ± 0.05 (4.45) |
| Sitosterol | 1.48 ± 0.03 (3.74) |
| Stigmast-4-en-3-one | 1.61 ± 0.11 (1.98) |
| Stigmasterol | 2.04 ± 0.12 (2.36) |
| Campesterol | 4.19 ± 0.05 (3.68) |
| Cholecalciferol (VD3) | 1.60 ± 0.22 (1.84) |
*n is the Hill coefficient as shown in the Hill equation (eqn (1)).