Table 2.
Association of lifestyle factors with liver function parameters in 8710 participants of the Guangzhou biobank cohort study
| Liver function parameters, adjusted β (95% CI) † | ||||
|---|---|---|---|---|
| ALT, IU/L | AST, IU/L | TBil, µmol/L | ALB, IU/L | |
| Smoking status | ||||
| Never | 0.00 | 0.00 | 0.00 | 0.00 |
| Former | 0.35 (-0.77, 1.76) | 0.29 (-0.50, 1.09) | -0.36 (-0.80, 0.08) | -0.29 (-0.61, 0.03) |
| Current | -1.32 (-2.56, -0.07) * | -0.99 (-1.77, -0.20) * | -1.33 (-1.77, -0.90) *** | -0.75 (-1.06, -0.43) *** |
| Alcohol use | ||||
| Never | 0.00 | 0.00 | 0.00 | 0.00 |
| Former | 2.41 (0.53, 4.29) * | 1.75 (0.56, 1.84) ** | -0.08 (-0.74, 0.57) | 0.34 (-0.14, 0.82) |
| Current | 1.17 (0.06, 2.28) * | 0.85 (0.19, 1.52) ** | 0.59 (0.20, 0.98) ** | 0.32 (0.03, 0.60) * |
| Physical activity | ||||
| Active | 0.00 | 0.00 | 0.00 | 0.00 |
| Moderate to inactive | 1.73 (0.71, 2.74) ** | 1.12 (0.66, 1.57) *** | 0.41 (0.06, 0.76) * | 0.15 (-0.11, 0.40) |
| Central obesity | ||||
| No | 0.00 | 0.00 | 0.00 | 0.00 |
| Yes | 4.98 (3.92, 6.04) *** | 0.85 (0.19, 1.52) * | 0.13 (-0.23, 0.50) | -0.15 (-0.42, 0.12) |
| General obesity | ||||
| No | 0.00 | 0.00 | 0.00 | 0.00 |
| Yes | 4.76 (3.56, 5.96) *** | 1.43 (0.68, 2.18) *** | 0.09 (-0.33, 0.51) | -0.18 (-0.49, 0.12) |
ALB = albumin, ALT = alanine aminotransferase, AST = aspartate aminotransferase, TBil = total bilirubin, CI = confidence interval.
†: Significant factors in the Table 1 were selected for analysis in this Table.
*P < 0.05; **P < 0.01; ***P < 0.001.