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. Author manuscript; available in PMC: 2025 May 27.
Published in final edited form as: J Med Chem. 2024 Jul 19;67(15):12534–12552. doi: 10.1021/acs.jmedchem.4c00411

Table 3.

Thermal shift data of front-pocket SAR for selected kinases. The selectivity was determined by dividing the number of kinases with thermal shifts higher than 50% of that of the reference compound by the total number of kinases investigated.a

graphic file with name nihms-2083027-t0013.jpg
a

See Table S1 for the full set of data.

b

See Table S1 for the references used for each kinase.