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. 2025 May 16;14(5):596. doi: 10.3390/antiox14050596
AAV Adeno-associated virus
Ahr aryl hydrocarbon receptor
ABCC2 ATP-binding cassette subfamily C member 2
ACl ATP citrate lyase
ACC1 acetyl-coenzyme A carboxylase 1
AKR1B1 aldo-keto reductase family 1B member 1
ALH1A1 aldehyde dehydrogenase family 1A member 1
AMD age-related macular degeneration
ATG5 autophagy-related 5
ATG7 autophagy-related 7
ATP6VOA1 V-ATPase
ARE antioxidant response element
BTB bric-a-brac domain
CALCOCO2 calcium-binding and coiled-coil domain 2
CFH complement factor H
cGS c-glutamate cysteine synthetase; FAS, fatty acid synthase
CLEAR coordinated lysosomal expression and regulation
CNC cap ‘n’ collar
CRL cullin–RING ligases
CRYAB Alpha-B crystallin
CTSB cathepsin B
CUL3 cullin 3
DMF dimethyl fumarate
G6PDH glucose-6-phosphatedehydrogenase
GPx glutathione peroxidase
Gpx8 glutathione peroxidase 8
GR glutathione reductase
GSTP1 glutathione peroxidase P1
HMOX1 heme oxygenase-1
HQ hydroquinone
IDH1 isocitratedehydrogenase 1
IVR intervening region
KEAP1 Kelch-like ECH-associated protein 1
LAMP2 lysosomal-associated membrane protein 2
ME malic enzyme
MMF monomethylfumarate
MTHFD2 methylenetetrahydrofolate dehydrogenase 2
mTOR mammalian target of rapamycin
mTORC1 mechanistic target of rapamycin complex 1
NFE2L2 NFE2-Like BZIP transcription factor-2
NF-kB nuclear factor-κB
NRF2 nuclear factor erythroid-2 related factor 2
OxS oxidative stress
PEDF pigment epithelium-derived factor
PGD phosphogluconate dehydrogenase
POS photoreceptor outer segments
PPAT phosphoribosyl pyrophosphate amidotransferase
PSMB7 proteasome subunitbtype-7
PTN pleiotrophin
p62 sequestosome 1
RPE retinal pigmented epithelium
RBX1 RING-box protein 1
ROS reactive oxygen species
SCD1 stearoyl-CoA desaturase
SFN sulforaphane
SNP single-nucleotide polymorphism
SOD superoxide dismutases
SQSTM1 sequestosome 1
SULT1A1 sulfotransferase family 1A member 1
sMAF small musculoaponeurotic fibrosarcoma oncogene homologue
tBH tert-butylhydroperoxide
TFEB transcription factor EB
TrxR thioredoxin reductase
UGT1A1 UDP glucuronosyltransferase family 1 member A1
ULK1 Unc-51-like autophagy-activating kinase 1
VAMP8 vesicular associated membrane protein 8
VEGF vascular endothelial growth factor