| −COO− | carboxylate anion |
| −COOH | carboxyl group |
| −OH | hydroxyl group |
| °C | degrees Celsius |
| µg/mL | microgram per milliliter (10−6 g per 10−3 L) |
| µg/L | microgram per liter (10−6 g per liter) |
| µmol | micromole (10−6 moles) |
| 1Δg O2 | singlet oxygen |
| 1O2 | singlet oxygen |
| 11-oxo-12-ene | a fragment of an oleanane molecule with a ketone group at C-11 and an unsaturated bond starting at C-12 atom |
| 17-COOH | carboxyl group located at the C-17 position of oleanane skeleton |
| 2α-OH | hydroxyl group located at the C-2 position of oleanane skeleton and at the α orientation |
| 3α-OH | hydroxyl group located at the C-3 position of oleanane skeleton and at the α orientation |
| 3β-OH | hydroxyl group located at the C-3 position of oleanane skeleton and at the β orientation |
| 3-Ac-OA | 3-acetyloleanolic acid |
| 3-oxo-OA | oleanonic acid, “3-oxooleanolic” acid (incorrect name) |
| 3-OH | hydroxyl group located at the C-3 position of oleanane skeleton |
| 3-Pht-OA | 3-phthaloyloleanolic acid |
| A2780 | ovarian cancer cells |
| AAE | Ascorbic Acid Equivalent |
| AAPH | (2,2′-azobis(2-amidinopropane) dihydrochloride) |
| ABTS | 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid |
| AcOADs | acetylated oleanolic acid dimers |
| AGEPs | advanced glycation end products |
| A-H | electron donor or proton donor |
| AhR | aryl hydrocarbon receptor |
| AKT/eNOS | protein kinase B/endothelial cell nitric oxide synthase |
| ALP | alkaline phosphatase |
| ALT | alanine aminotransferase |
| AMPK | adenosine monophosphate-activated protein kinase |
| ARE | antioxidant response element |
| B16 | murine melanoma cell line |
| BA | betulinic acid |
| Bax | Bcl-2-associated protein x, B-cell lymphoma 2-associated protein x |
| BHT | butylated hydroxytoluene |
| Br-X-Br | α,ω-dihalogenoalkane or α,ω-dihalogenoalkene |
| BUN | blood urea nitrogen |
| C-12=C-13 | double bond between carbon atoms at the 12 and 13 positions of oleanane skeleton |
| C-2,3 | arrangement of two identical elements at the C-2 and C-3 position of the oleanane molecule |
| C-3 (C-5, etc.) | carbon atom at the position number 3 (number 5, etc.) of oleanane skeleton |
| C57BL/6 | common inbred strain of laboratory mouse |
| CAT | catalase |
| CCl4/NADPH | carbon tetrachloride/nicotinamide adenine dinucleotide phosphate |
| CHP | cumine hydroperoxide (correct name: cumene hydroperoxide) |
| CIRI | cerebral ischemia-reperfusion injury |
| CK-MB | creatine kinase-myocardial band |
| Cl-Au-PPh3 | chloro(triphenylphosphine)gold(I); correct abbreviation: (Ph3P)AuCl or Au(PPh3)Cl) |
| Co(II)/EDTA | cobalt(II) ions and ethylenediaminetetraacetic acid |
| COX-2 | Cyclooxygenase-2; prostaglandin-endoperoxide synthase 2 |
| Cu2+ | element copper in its +2 oxidation state |
| CYO1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DMAPP | dimethylallyl pyrophosphate |
| CML | carboxymethyl lysine |
| DMF | N,N-dimethylformamide |
| DN | Diabetic nephropathy |
| DNA | deoxyribonucleic acid |
| Dox | doxorubicin |
| DPPH | 1,1-diphenyl-2-picrylhydrazyl |
| DPPH• | 1,1-diphenyl-2-picrylhydrazyl radical |
| DSS | Dahl-salt sensitive (rats) |
| e− | electron, electron donor |
| ECM | extracellular matrix |
| epi-OA | epi-oleanolic acid |
| e.g., | exempli gratia (Lat.), for example (Eng.) |
| ER | endoplasmic reticulum |
| ERK | extracellular signal-regulated kinase |
| ERS | endoplasmic reticulum stress |
| et al. | et alia (Lat.), and others (Eng.) |
| etc. | et cetera (Lat.), and so on (Eng.) |
| Fe2+ | element iron in its +2 oxidation state |
| Fe3+ | element iron in its +3 oxidation state |
| [Fe(TPTZ)2]3+ | ferric-tripyridyltriazine |
| [Fe(TPTZ)2]3+ | reduced ferric-tripyridyltriazine |
| FRAP | Ferric Reducing Antioxidant Power |
| FTIR | Fourier transform infrared spectroscopy |
| CGLc | glutamate-cysteine ligase catalytic subunit |
| GA | glycyrrhetinic acid |
| GS | Granny Smith (apple variety) |
| GSH | glutathione in its reduced form |
| GSH/GSSG | reduced to oxidized glutathione |
| GSH-Px | glutathione peroxidase |
| H2O2 | hydrogen peroxide |
| HCT-116 | colon cancer cell line |
| HDL | high-density lipoprotein |
| HFF | high fat and fructose |
| HO-1 | heme oxygenase-1 |
| HPLC | High-Performance Liquid Chromatography |
| HUVEC | human umbilical vein endothelial cells |
| IC50 | minimum inhibitory concentration |
| i.e., | id est (Lat.), that is, it means (Eng.) |
| IFN-γ | interferon-γ |
| IL-1β | interleukin-1 beta |
| IL-6 | interleukin-6 |
| IL-10 | interleukin 10 |
| iNOS | inducible nitric oxide synthase |
| IPP | isopentenyl pyrophosphate |
| I/R | ischemia/reperfusion |
| JAK-STAT | Janus kinase/signal transducers and activators of transcription |
| JNK | cellular Jun N-terminal kinase |
| K2CO3 | potassium carbonate |
| K562 | chronic myelogenous leukemia |
| Keap1 | Kelch-like ECH-associated protein 1 |
| KIM-1 | kidney injury molecule 1 |
| L1210 | mouse lymphocytic leukemia cell line |
| LC3-II | lipidated form of microtubule-associated protein 1 light chain |
| LDH | lactate dehydrogenase |
| LDL | low density lipoprotein |
| Lipo-OANPs | oleanolic acid loaded liposomal nanoparticles |
| LPS | lipopolysaccharides |
| LX-2 | human hepatic stellate cell line |
| MAPK | mitogen-activated protein kinase, MAP-kinase |
| MCF-10A | human breast epithelial cell line |
| MDA | malondialdehyde |
| MDA-MB-231 | triple negative human epithelial breast cancer cells |
| MEP | methylerythritol phosphate |
| MEs | microemulsions |
| ME-1, ME-2 | microemulsion no. 1, microemulsion no. 2 |
| mg | milligram (10−3 g) |
| mg/g | milligram per gram (10−3 g per gram) |
| mg/kg | milligram per kilogram (10−3 g per 103 g) |
| MPO | myeloperoxidase |
| miRNAs | key regulators of gene expression, play essential roles in the pathobiology of cancer |
| mmol | millimole (10−3 mole) |
| MMP1 | matrix metalloproteinase 1 |
| MMPs | matrix metalloproteinases |
| MPE | mango peel extract |
| MVA | mevalonic acid |
| MWCNTs/SPE | screen-printed electrode modified with multi-walled carbon nanotubes |
| N2 | nitrogen gas |
| NAC | N-acetylcysteine |
| NADPH | nicotinamide adenine dinucleotide phosphate |
| NaHMDS | sodium bis(trimethylsilyl)amide |
| nano-OA | nanoparticles of oleanolic acid |
| NBT | nitroblue tetrazolium salt |
| n.d. | no data |
| N-EGR | non-enzymatic glycation reaction |
| NF-κB | nuclear factor kappa B |
| nm | nanometer (10−9 m) |
| nM | nanomole (10−9 moles) |
| NE | nanoemulsion |
| NO | nitric oxide |
| NOX | NADPH-oxidase |
| Nrf2 | nuclear erythroid 2-related transcription factor |
| NQO1 | quinone oxidoreductase |
| •O2− | superoxide radical |
| •OH | hydroxyl radical |
| OA | oleanolic acid |
| OADs | oleanolic acid dimers |
| OANF | oleanolic acid nanofibers |
| OANPs | oleanolic acid nanoparticles |
| ODG/R | oxygen and glucose deprivation and reoxygenation |
| ORAC | Oxygen Radical Absorbance Capacity |
| P12 | pheochromocytoma tumor of the rat adrenal medulla |
| p62 | stress-inducible protein |
| PAMPA | parallel artificial membrane permeability assay |
| pH | the negative decadic logarithm of the proton activity in the solution under scrutiny |
| PI3K/AKT | phosphatidylinositol 3-kinase and activated protein kinase |
| pKa | the negative decadic logarithm of acid dissociation constant |
| PM | particulate matter |
| PM2 | particulate matter with a diameter of 2.5 μm or less |
| PM10 | particulate matter with a diameter of 10 μm or less |
| PRX-1 | peroxidoxin 1 |
| QZG | human fetal liver cell line |
| RAW 264.7 | murine macrophages |
| RD | Red Delicious (apple variety) |
| RG | Royal Gala (apple variety) |
| ROS | reactive oxygen species |
| rpm | revolutions per minute |
| RSA | radical scavenging sctivity |
| SDH | succinate dehydrogenase |
| SGOT | serum glutamic-oxaloacetic transaminase |
| SGP | serum glutamic pyruvic transaminase |
| SHR | spontaneously hypertensive rats |
| SMAD | Suppressor of Mothers Against Decapentaplegic |
| SOD | superoxide dismutase |
| SRB | sulforhodamine-B |
| tBHP | tert-butyl hydroperoxide |
| TAC | total antioxidant capacity |
| TE | trolox equivalent |
| TEM | transmission electron microscopy |
| TGF-β/SMAD2/3 | transforming growth factor-β/SMAD 2 and SMAD 3 |
| TGR5 | Takeda G protein-coupled receptor 5 |
| THF | tetrahydrofurane |
| TNF-α | tumor necrosis factor alpha |
| Trx | thioredoxin |
| TrxR | thioredoxin reductase |
| UA | ursolic acid |
| UUO | unilateral ureteral obstruction |
| XRD | X-ray diffraction |