Abbreviation	Full Term
Aβ	Beta-amyloid
ACEis	Angiotensin-converting enzyme inhibitors
ACAS	Asymmetrical carotid artery stenosis
AD	Alzheimer’s disease
Anti-BACE1	Beta-Site APP Cleaving Enzyme 1
APP	Amyloid precursor protein
ARBs	Angiotensin receptor blockers
ATVs	Antibody transport vehicles
BCAL	Bilateral carotid artery ligation
BCAS	Bilateral common carotid artery stenosis
BBB	Blood–brain barrier
CAA	Cerebral amyloid angiopathy
CBF	Cerebral blood flow
CNS	Central nervous system
CSVD	Cerebral small vessel disease
DIAN-TU	Dominantly inherited Alzheimer Network Trials Unit
DTI	Diffusion tensor imaging
ECM	Extracellular matrix
ENIGMA	Enhancing Neuro-Imaging Genetics through Meta-Analysis
eNOS	Endothelial nitric oxide synthase
Gal-3	Galectin-3
HIF-1α	Hypoxia-inducible factor 1-α
IGF-1	Insulin-like growth factor 1
MMP	Matrix metalloproteinases
NfL	Neurofilament light chain
NMDAR	N-methyl-D-aspartate receptor
NO	Nitric oxide
NOC-18	NO donor 2,2′-(hydroxynitrosohydrazino)bis-ethanamine
Nrf2	Nuclear factor erythroid 2–related factor 2
NVU	Neurovascular unit
PDGF	Platelet-derived growth factor
RAS	Renin-angiotensin system
ROS	Reactive oxygen species
SAH	Subarachnoid hemorrhage
SHRSP	Spontaneously hypertensive stroke-prone
SMARRT	Systemic Multi-Domain Alzheimer’s Risk Reduction Trial
SPRINT-MIND	Systolic Blood Pressure Intervention Memory Trial and Cognition in Decreased Hypertension
SVD	Small vessel disease
TIA	Transient ischemic attacks
VaD	Vascular dementia
VCID	Vascular contributions to cognitive impairment and dementia
VICCCS	Vascular Impairment of Cognition Classification Consensus Study
VSMC	Vascular smooth muscle cells