Treg	Regulatory T lymphocytes
CD4	Cluster of Differentiation 4
CD25	Cluster of Differentiation 25
FOXP3	Forkhead box P3
TGFβ	Transforming Growth Factor Beta
IL-10	Interleukin 10
IL-1	Interleukin 1
MDSC	Myeloid-Derived Suppressor Cells
M-MDSC	Monocyte-like Myeloid-Derived Suppressor Cells
PMN-MDSC	Polymorphonuclear Myeloid-Derived Suppressor Cells
CD8+	Cytotoxic T lymphocyte
NK	Natural Killer cells
PDAC	Pancreatic Ductal Adenocarcinoma
GM-CSF	Granulocyte-Macrophage Colony-Stimulating Factor
IL-13	Interleukin 13
HIFs	Hypoxia-Inducible Factors
TAMs	Tumor-Associated Macrophages
TNFα	Tumor Necrosis Factor Alpha
HIF2	Hypoxia-Inducible Factor 2
CAFs	Cancer-Associated Fibroblasts
myCAF	Myofibroblastic Cancer-Associated Fibroblasts
iCAF	inflammatory Cancer-Associated Fibroblasts
apCAF	Antigen-presenting Cancer-Associated Fibroblasts
ECM	Extracellular Matrix
CK-19	Cytokeratin-19
SOX9	SRY-Box Transcription Factor 9
FOLFIRINOX	Fluorouracil, Leucovorin, Irinotecan, Oxaliplatin
GnP	Gemcitabine and Nab-Paclitaxel
R-PDAC	Resectable Pancreatic Ductal Adenocarcinoma
BR-PDAC	Borderline Resectable Pancreatic Ductal Adenocarcinoma
MSI-high	Microsatellite Instability-high
PD-L1	Programmed Death-Ligand 1
MEK1/2	Mitogen-Activated Protein Kinase ½
CAR-T	Chimeric Antigen Receptor T-cells
CEA	Carcinoembryonic Antigen
PSCA	Prostate Stem Cell Antigen
MSLN	Mesothelin
ICIs	Immune Checkpoint Inhibitors
CXCL12	C-X-C Motif Chemokine Ligand 12
CCL2	C-C motif chemokine 2
NGF	Nerve Growth Factor
GDNF	Glial Cell-Derived Neurotrophic Factor
HGF	Hepatocyte Growth Factor
STAT3	Signal Transducer and Activator of Transcription 3
β2	Beta-2 Adrenergic Receptor
TME	Tumor Microenvironment
OS	Overall Survival
DFS	Disease-Free Survival
PAR-2	Protease-Activated Receptor 2
ICPs	Immune Checkpoints
TANs	Tumor-Associated Neutrophils
FAP	Fibroblast Activation Protein
ERK	Extracellular Signal-Regulated Kinase
TILs	Tumor-Infiltrating Lymphocytes
PC	Pancreatic Cancer
CK-19	Cytokeratin-19
SEER	Surveillance, Epidemiology, and End Results Programme
PSC	Pancreatic Stellate Cells
PDGF	Platelet-derived growth factor
FGF	fibroblast growth factor
CTGF	Connective tissue growth factor
αSMA	α-smooth muscle actin
IGF1	Insulin-like growth factor 1
VEGF	Vascular endothelial growth factor
FSP1	Fibroblasts-specific protein 1
ETM	Endothelial-to-mesenchymal transition
SDF-1	Stromal-derived factor-1
ROS	Reactive Oxygen Species
NOXs	NADPH oxidases
ER	Endoplasmatic Reticulum
siRNAs	Small interfering RNAs
SMA+	Alpha-smooth muscle actin
SHH,	Sonic Hedgehog Homolog
Ptch	Patched transmembrane protein
SMO	Smoothened transmembrane protein
GM-CSF	Granulocyte-macrophage colony-stimulating factor
TIMP	Matrix-metalloproteinases inhibitors
PDX	Patient-dervied xenografts
RA	Retinoid acid
ATRA	All-trans-retinoid-acid
HMGA1	High mobility group A1
ADM	Acinar-to-ductal metaplasia
GFRA1	GDNF family receptor alpha 1
PNI	Perineural invasion
L1CAM	L1 cell adhesion molecule
CSF1	Colony stimulating factor 1
ACh	Acetylcholine
AChR	Acetylcholine receptor
PAR-2	Protease-activated receptor 2
LTS	Long-time survivors
STS	Short-time survivors
3-IAA	Indole-3-acetic acid
GP	Gammaproteobacterium
NSCLC	Non-small cell lung cancer
RCC	Renal cell cancer
TSAs	Tumor-specific antigens
GVAX	Pancreatic cancer cell line-based vaccine
BIRC5	Baculoviral IAP Repeat Containing 5
CCND1	Cyclin D1
CDH1	Cadherin 1
CD74	Cluster of Differentiation 74
COL6A3	Collagen type VI alpha three chain
CTHRC1	Collagen triple helix repeat containing 1
IL-13RA2	Interleukin 13 receptor subunit alpha 2
LRP1	Low-density lipoprotein receptor-related protein 1
MAP1LC3A/B	Microtubule-associated protein one light chain three alpha/beta
MDK	Midkine
MYBL2	MYB proto-oncogene like 2
MYC	MYC proto-oncogene
PODXL	Podocalyxin-like protein
PTN	Pleiotrophin
SDC2	Syndecan 2
SDC3	Syndecan 3
SNCG	Synuclein gamma
TIMP2	Tissue inhibitor of metalloproteinases 2
VGF	VGF nerve growth factor
WASL	WASP-like actin nucleation-promoting factor
FAS	FAS cell surface death receptor
POP1	Processing of precursor 1, ribonuclease P/MRP subunit
CADM4	Cell adhesion molecule 4
HPGD	15-hydroxyprostaglandin dehydrogenase
CD11b	Cluster of differentiation 11b
VEGFR1	Vascular endothelial growth factor receptor 1
VEGFR2	Vascular endothelial growth factor receptor 2
VEGFR3	Vascular endothelial growth factor receptor 3
CSF-1R	Colony-stimulating-factor receptor 1
TLR3	Toll-like receptor 3
PARP1	Poly(ADP-ribose) polymerase 1
PARP2	Poly(ADP-ribose) polymerase 2
LRRC15	Leucine-rich repeat containing 15 protein
IGF1R	Insulin-like growth factor 1 receptor
HA	Hyaluronic acid
LIF	Leukemia inhibitory factor
FOLFIRINOX	5-Fluorouracil, Irinotecan, Oxaliplatin, Leucovorin