Training Cohort			Internal Validation Cohort			External Validation Cohort
Characteristics		Healthy Development	Developmental Impairment	p	HealthyDevelopment	DevelopmentalImpairment	p	Healthy Development	Developmental Impairment	p
		N = 107 (%)	N = 143 (%)		N = 43 (%)	N = 62 (%)		N = 72 (%)	N = 80 (%)
Premature infant
NBNA	High	16 (14.95)	26 (18.18)	0.706	8 (18.60)	9 (14.52)	0.7255	36 (50.00)	43 (53.75)	0.2584
	Middle	32 (29.91)	45 (31.47)		14 (32.56)	18 (29.03)		21 (29.17)	28 (35.00)
	Low	59 (55.14)	72 (50.35)		21 (48.84)	35 (56.45)		15 (20.83)	9 (11.25)
Sex	Female	37 (34.58)	56 (39.16)	0.5423	21 (48.84)	33 (53.23)	0.8073	39 (54.17)	23 (28.75)	0.0025
	Male	70 (65.42)	87 (60.84)		22 (51.16)	29 (46.77)		33 (45.83)	57 (71.25)
Gestational Age	<28 W	8 (7.48)	8 (5.59)	0.0073	4 (9.30)	8 (12.90)	0.0016	5 (6.94)	16 (20.00)	0.0003
	28–32 W	24 (22.43)	52 (36.36)		6 (13.95)	28 (45.16)		19 (26.39)	36 (45.00)
	32–34 W	16 (14.95)	33 (23.08)		21 (48.84)	12 (19.35)		16 (22.22)	15 (18.75)
	34–37 W	59 (55.14)	50 (34.97)		12 (27.91)	14 (22.58)		32 (44.44)	13 (16.25)
Delivery Mode	Cesarean Section	84 (78.50)	105 (73.43)	0.4376	34 (79.07)	43 (69.35)	0.3775	57 (79.17)	64 (80.00)	1
	Natural birth	23 (21.50)	38 (26.57)		9 (20.93)	19 (30.65)		15 (20.83)	16 (20.00)
Risk Factors	No	68 (63.55)	59 (41.26)	0.0008	35 (81.40)	20 (32.26)	<0.0001	50 (69.44)	36 (45.00)	0.0041
	Yes	39 (36.45)	84 (58.74)		8 (18.60)	42 (67.74)		22 (30.56)	44 (55.00)
Primary caregivers
Apartment	City	80 (74.77)	112 (78.32)	0.6593	31 (72.09)	51 (82.26)	0.3869	65 (90.28)	71 (88.75)	0.4191
	Towns	10 (9.35)	14 (9.79)		4 (9.30)	5 (8.06)		6 (8.33)	5 (6.25)
	Villages	17 (15.89)	17 (11.89)		8 (18.60)	6 (9.68)		1 (1.39)	4 (5.00)
Caregivers Age	<20 Y	31 (28.97)	44 (30.77)	0.7018	7 (16.28)	16 (25.81)	0.2779	18 (25.00)	33 (41.25)	0.1167
	20–30 Y	71 (66.36)	94 (65.73)		34 (79.07)	42 (67.74)		49 (68.06)	43 (53.75)
	31–40 Y	5 (4.67)	4 (2.80)		1 (2.33)	4 (6.45)		5 (6.94)	3 (3.75)
	41–50 Y	0 (0)	1 (0.70)		1 (2.33)	0 (0.00)		0 (0.00)	1 (1.25)
Educational level	Primary and lower	4 (3.74)	2 (1.40)	0.0004	2 (4.65)	0 (0.00)	0.008	1 (1.39)	4 (5.00)	0.0003
	Middle or high school	88 (82.24)	128 (89.51)		38 (88.37)	55 (88.71)		56 (77.78)	68 (85.00)
	College and above	15 (14.02)	13 (9.09)		3 (6.98)	7 (11.29)		15 (20.83)	8 (10.00)
Monthly Household Income	<2 K	5 (4.67)	2 (1.40)	0.0472	0 (0.00)	3 (4.84)	0.0572	5 (6.94)	2 (2.50)	0.6123
	2–6 K	29 (27.10)	47 (32.87)		13 (30.23)	23 (37.10)		13 (18.06)	14 (17.50)
	7–10 K	40 (37.38)	67 (46.85)		15 (34.88)	27 (43.55)		36 (50.00)	44 (55.00)
	>10 K	33 (30.84)	27 (18.88)		15 (34.88)	9 (14.52)		18 (25.00)	20 (25.00)
Working Condition	Employee	79 (73.83)	102 (71.33)	0.4641	33 (75.00)	36 (58.06)	0.1397	56 (77.78)	62 (77.5)	0.8474
	Unemployed	28 (26.17)	41 (28.67)		10 (22.73)	26 (41.94)		16 (22.22)	18 (22.50)
Caregiving Experience	No	79 (73.83)	127 (88.81)	0.0036	20 (46.51)	59 (95.16)	<0.0001	32 (44.44)	65 (81.25)	<0.0001
	Yes	28 (26.17)	16 (11.19)		23 (53.49)	3 (4.84)		40 (55.56)	15 (18.75)
Caregiving Knowledge	No	76 (71.03)	129 (90.21)	0.0002	19 (44.19)	56 (90.32)	<0.0001	35 (48.61)	56 (70.00)	<0.0001
	Yes	31 (28.97)	14 (9.79)		24 (55.81)	6 (9.68)		37 (51.39)	24 (30.00)
Length of Stay	<14 D	39 (36.45)	41 (28.67)	0.4142	9 (20.93)	22 (35.48)	0.1818	52 (72.22)	52 (65.00)	0.6253
	14–23 D	34 (31.78)	49 (34.27)		16 (37.21)	23 (37.10)		14 (19.44)	19 (23.75)
	>23 D	34 (31.78)	53 (37.06)		18 (41.86)	17 (27.42)		6 (8.33)	9 (11.25)
Caregiver Sex	Female	91 (85.05)	111 (77.62)	0.1894	35 (81.40)	40 (64.52)	0.0963	60 (83.33)	66 (82.50)	1
	Male	16 (14.95)	32 (22.38)		8 (18.60)	22 (35.48)		12 (16.67)	14 (17.50)
Marital Status	Married or Cohabiting	102 (95.3)	138 (96.50)	0.8859	40 (93.02)	62 (100.00)	0.1299	72 (100.00)	79 (98.75)	1
	Single	5 (4.67)	5 (3.50)		3 (6.98)	0 (0.00)		0 (0.00)	1 (1.25)
Insurance payment	Commercial Insurance	7 (6.54)	6 (4.20)	0.133	2 (4.65)	5 (8.06)	0.4469	0 (0.00)	1 (1.25)	0.3177
	Rural Medical Care	18 (16.82)	36 (25.17)		6 (13.95)	13 (20.97)		55 (76.39)	56 (70.00)
	Self-pay	9 (8.41)	20 (13.99)		8 (18.60)	6 (9.68)		12 (16.67)	11 (13.75)
	Social Insurance	73 (68.22)	81 (56.64)		27 (62.79)	38 (61.29)		5 (6.94)	12 (15.00)
Relationship with Newborn	Father	25 (23.36)	36 (25.17)	0.7037	9 (20.93)	16 (25.81)	0.8021	21 (29.17)	20 (25.00)	0.5874
	Mother	76 (71.03)	102 (71.33)		33 (76.74)	44 (70.97)		50 (69.44	57 (71.25)
	Grandparent	6 (5.61)	5 (3.50)		1 (2.33)	2 (3.23)		1 (1.39)	3 (3.75)
Other Caregivers	No	23 (21.50)	79 (55.24)	<0.0001	11 (25.58)	41 (66.13)	<0.0001	10 (13.89)	42 (52.50)	<0.0001
	Yes	84 (78.50)	64 (44.76)		32 (74.42)	21 (33.87)		62 (86.11)	38 (47.50)