SAM |
S-adenosyl-methionine |
TME |
Tumor microenvironment |
MATs |
Methionine adenosyltransferases |
SAH |
S-Adenosylhomocysteine |
5-MTHF |
5-methyltetrahydrofolate |
MTA |
Methylthioadenosine |
MTAP |
Methylthioadenosine phosphorylase |
5,10-MTHF |
5,10-methylene tetrahydrofolate |
mTORC1 |
Mechanistic target of rapamycin complex 1 |
DNMTs |
DNA methyltransferases |
CpG |
Cytosine–phosphate–guanine |
DAPK1 |
Death-associated protein kinase 1 |
PUMA |
P53 upregulated modulator of apoptosis |
BNIP3 |
BCL2 interacting protein 3 |
lncRNA |
Long non-coding RNA |
PET |
Positron emission tomography |
WTAP |
Wilms tumor 1-associated protein |
SLC |
Solute carriers |
PD-L1 |
Programmed cell death ligand 1 |
VISTA |
V-domain immunoglobulin suppressor of T cell activation |
ATAD2 |
ATPase family AAA domain-containing protein 2 |
PRMT |
Protein arginine methyltransferase |
ACSL3 |
Acyl-CoA synthetase long chain family member 3 |
TNBC |
Triple-negative breast cancer |
PARP |
Poly (ADP-ribose) polymerase |
CSCs |
Tumor stem cells |
ROS |
Reactive oxygen species |
MCR |
Methionine/cystine restriction |
CHAC1 |
Cation transport regulator homolog 1 |
MR |
Methionine restriction |
MAPK14 |
Mitogen-activated protein kinase P38 |
MK2 |
MAPK-activated protein kinase 2 |
GSH |
Glutathione |
NF-κB |
Nuclear factor kappa B |
PD-1 |
Programmed cell death protein 1 |
CAR-T |
Chimeric antigen receptor T-cell |
cGAS |
Cyclic GMP-AMP synthase |
UHRF1 |
Ubiquitin-like with plant homeodomain and RING finger domains 1 |
STING |
Stimulator of interferon genes |
MGL |
Methionine γ lyase |
hCGL |
Human enzyme cystathionine-γ-lyase |
MRD |
Methionine restriction diet |
rMETase |
Recombinant methioninase |