ACG	American College of Gastroenterology
AEs	adverse events
CAP	community-acquired pneumonia
CI	confidence interval
DGER	duodeno-gastro-esophageal reflux
ECL	Enterochromaffin-like
EE	erosive esophagitis
FDA	Food and Drug Administration
FSSG	Frequency Scale for Symptoms of Gastroesophageal Reflux Disease
GERD	gastroesophageal reflux disease
H+/K+-ATPase	hydrogen–potassium ATPase
H2RAs	H2 receptor antagonists
HRM	high-resolution manometry
HRT	Holding Time Radio
JADER	Japanese Adverse Drug Event Report
LA	Los Angeles
LES	lower esophageal sphincter
MAD	multiple ascending dose
NERD	non-erosive reflux disease
NETs	neuroendocrine tumors
PCABs	potassium-competitive acid blockers
PPIs	proton pump inhibitors
PSQI	Pittsburgh Sleep Quality Index
RCT	randomized controlled trial
RE	reflux esophagitis
SAD	single ascending dose
SAEs	serious adverse events
SUCRA	Surface Under the Cumulative Ranking Curve