TABLE 4.

Distribution of mild, moderate and severe keratoconus classifications for individuals with Down syndrome identified with one or both eyes as suspect for keratoconus, compared with the distribution of participants in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) study with known keratoconus.

Steep Keratometric Reading	Individuals with Down syndrome with both eyes available for analysis—One or more eyes detected as suspect for keratoconus	CLEK keratoconus subjects
	% (n)	% (n)48
Mild (<45 D)	7.1 (2)	4.6 (55)
Moderate (45–52 D)	89.3 (25)	48.7 (586)
Severe (>52 D)	3.6 (1)	46.7 (562)

Note: Data from Marsack et al.46