Table 1.

Genetic variants in the CYP2C19 and CYP2D6 genes identified in the Estonian Biobank. Positions are according to GRCh37

rs-number	Position	Ref.	Alt.	MAF % (EstBB)	Amino acid exchange
CYP2C19
rs1466428833	Chr10:96,535,156	T	G	0.02	F114C
rs1361528097	Chr10:96,540,264	T	G	0.02	C164G
rs140278421	Chr10:96,540,331	G	A	0.04	R186H
rs148247410	Chr10:96,541,688	C	G	0.02	H251Q
rs1431015009	Chr10:96,580,257	A	T	0.02	K275M
rs1393133490	Chr10:96,580,323	C	T	0.02	A297V
Not available	Chr10:96,602,648	T	C	0.02	M339T
CYP2D6
rs1230912765	Chr22:42,525,143	G	A	0.02	R133C
rs1058171	Chr22:42,523,928	C	T	0.02	D301N
Not available	Chr22:42,523,916	C	T	0.02	A305T
Not available	Chr22:42,523,889	G	T	0.02	L314M
rs28371733	Chr22:42,522,916	CG	C	0.02	E418NfsTer11
rs757396767	Chr22:42,522,982	TGA	T	0.10	L395HfsTer11
rs730882170	Chr22:42,523,847	GCACATCCGG ATGTAGGATC	G	0.02	M321IfsTer12
rs750439337	Chr22:42,524,820	T	TC	0.92	E211GfsTer43