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. 2025 May 28;29(11):e70634. doi: 10.1111/jcmm.70634

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© 2025 The Author(s). Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Proteomic profiling of H1299 cells with OVOL1 knockdown. (A) Coomassie brilliant blue staining of proteins immunoprecipitated with anti‐OVOL1 antibody from total cell lysates of H1299 cells. (B) PCA scores plot for H1299 cells with or without OVOL1 knockdown. (C) Volcano plot of the differential gene expression distribution. (D) Hierarchical clustering results for proteins in shControl versus shOVOL1 group. (E) GO term enrichment analysis of significant proteins. (F) KEGG pathway enrichment analysis of significant proteins.