Table 2.
Statistical analysis of clinical characteristics.
| Feature name | Total sample size (N=92,681) | Non-colorectal adenoma group (N=90,212) | Colorectal adenoma group (N=2,469) | P-value |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age, mean(SD) | 49.1 (15.7) | 48.8 (15.7) | 59.4 (14.7) | <0.05 |
| Male, n (%) | 42765 (46.1) | 41407 (45.9) | 1358 (55.0) | <0.05 |
| Signs and symptoms | ||||
| Blood in stool, n (%) | 5155 (5.6) | 4691 (5.2) | 464 (18.8) | <0.05 |
| Nausea, n (%) | 7692 (8.3) | 7578 (8.4) | 114 (4.6) | <0.05 |
| Abdominal pain, n (%) | 12876 (13.9) | 12449 (13.8) | 427 (17.3) | <0.05 |
| Stool abnormalities, n (%) | 32319 (34.9) | 31304 (34.7) | 1015 (41.1) | <0.05 |
| family history | ||||
| Colon cancer, n (%) | 583 (0.6) | 541 (0.6) | 42 (1.7) | <0.05 |
| Colon polyps, n (%) | 4465 (4.8) | 4060 (4.5) | 405 (16.4) | <0.05 |
| Hypertension, n (%) | 9108 (9.8) | 8570 (9.5) | 538 (21.8) | <0.05 |
| Diabetes, n (%) | 4006 (4.3) | 3789 (4.2) | 217 (8.8) | <0.05 |
| Inspection Indicators | ||||
| Hemoglobin (g/L, mean(SD)) | 140.8 (15.7) | 140.9 (15.7) | 136.9 (16.6) | <0.05 |
| Fecal occult blood test, n (%) | 3817 (4.1) | 3518 (3.9) | 299 (12.1) | <0.05 |
| Cholesterol(mmol/L, mean(SD)) | 4.6 (1.0) | 4.6 (1.0) | 4.6 (1.0) | 0.362 |
| Triglycerides(mmol/L, mean(SD)) | 1.3 (0.6) | 1.3 (0.6) | 1.3 (0.6) | 0.094 |
| Lipoprotein A (mg/L, Median [Q1,Q3]) | 90.0 [43.0,182.0] | 86.0 [41.0,176.0] | 103.5 [47.0,196.2] | <0.05 |
| Serum uric acid (umol/L,mean(SD)) | 312.1 (83.3) | 312.5 (83.2) | 303.2 (86.1) | <0.05 |
| Creatinine(umol/L, mean(SD)) | 76.1 (14.2) | 76.2 (14.1) | 73.7 (15.4) | <0.05 |
| Glycosylated hemoglobin (%, mean(SD)) | 5.8 (0.5) | 5.8 (0.5) | 5.9 (0.5) | <0.05 |
| CEA (ng/ml, mean(SD)) | 2.0 (1.1) | 2.0 (1.1) | 2.2 (1.2) | <0.05 |
| CA19-9 (IU/L, mean(SD)) | 10.6 (7.1) | 10.6 (7.2) | 10.9 (6.9) | 0.158 |