FIGURE 6.

Transition probabilities of AO onset over repeated WCS exposures. Whisker-box plots of transition probabilities of AO onset calculated using a virtually generated dataset with dynamic BN modeling. Probabilities were calculated by extracting all possible combinations of three of the six donors (20 combinations in total) and assuming the activation/onset of KEs and AO had occurred when the log2FC of the response relative to the air-exposure control was >2. Exp; exposure repetition, KE; key event, AO; adverse outcome.