Table 2.

Comparison of outcome variables between the 2 groups at each time point.

Variable	T0		T1		T2		T3		T4		T5		T6		T7
	Z	P value	Z	P value	Z	P value	Z	P value	Z	P value	Z	P value	t test (df)	P value	t test (df)	P value
TAIa total score	–0.591	.55	–1.342	.18	–2.014	.04	–3.892	<.001	–3.799	<.001	–4.474	<.001	–5.449 (92)	<.001	–5.685 (92)	<.001
Erratic nonadherent dimension of TAI	–0.191	.85	–0.735	.46	–0.336	.74	–2.344	.02	–2.690	.007	–3.271	.001	–5.289 (92)	<.001	–4.951 (92)	<.001
Deliberate nonadherent dimension of TAI	–1.057	.29	–0.859	.39	–2.001	.045	–4.106	<.001	–3.919	<.001	–2.807	.005	–3.310 (92)	.001	–3.963 (92)	<.001
Accuracy rate of inhaler technique (%)	–0.041	.97	–4.489	<.001	–3.647	<.001	–3.617	<.001	–3.877	<.001	–4.977	<.001	–5.456 (92)	<.001	–5.269 (92)	<.001
Severity of dyspnea (mMRC)b	–0.528	.60	–0.254	.80	–0.491	.62	–1.361	.17	–1.880	.06	–2.260	.02	–2.038 (92)	.04	–2.085 (92)	.04
HRQoLc of patients with COPDd (CATe score)	–1.954	.05	–0.513	.61	1.373	.17	1.678	.10	2.173	.03	3.156	.002	2.939 (92)	.004	3.302 (92)	.002
Health literacy of patients with COPD (COPD-Qf score)	–0.509	.61	–2.551	.01	–2.799	.006	–4.206	<.001	–3.824	<.001	–4.053	<.001	–5.990 (92)	<.001	–6.129 (92)	<.001

^aTAI: Test of Adherence to Inhalers.

^bmMRC: modified Medical Research Council.

^cHRQoL: health-related quality of life.

^dCOPD: chronic obstructive pulmonary disease.

^eCAT: Chronic Obstructive Pulmonary Disease Assessment Test.

^fCOPD-Q: Chronic Obstructive Pulmonary Disease Knowledge Questionnaire.