Table 2.
The results of a multilevel linear regression model examining the associations between drug categories, countries, sectors and COVID times on the square root of drug consumption. Coefficients and their p-values
| Stratification parameters | β | 95% CI | P valuea |
|---|---|---|---|
| Intercept | 0.91 | 0.76, 1.06 | < 2e-16 *** |
| Drug categories | |||
| Carbapenems | Referent | ||
| Polymyxins | −0.17 | −0.35, −0.002 | 0.04 * |
| Tetracyclines | 0.4 | 0.25, 0.55 | 3.22e-07*** |
| Penicillins | 1.08 | 0.93, 1.23 | < 2e-16 *** |
| Other beta-lactams | −0.01 | −0.16, 0.14 | 0.91 |
| Sulfonamides/trimethoprim | −0.06 | −0.21, 0.09 | 0.44 |
| Macrolides, lincosamides and streptogramins | 0.05 | −0.1, 0.2 | 0.54 |
| Quinolones | −0.08 | −0.24, 0.07 | 0.27 |
| Other antibacterials | 0.20 | 0.05, 0.35 | 0.01 ** |
| Countries | |||
| Denmark | Referent | ||
| Finland | 0.06 | −0.03, 0.16 | 0.19 |
| Iceland | 0.08 | −0.01, 0.18 | 0.08 |
| Norway | −0.004 | −0.09, 0.09 | 0.93 |
| Sweden | −0.06 | −0.15, 0.04 | 0.25 |
| Sectors | |||
| Community | Referent | ||
| Hospital | −0.76 | −0.83, −0.69 | < 2e-16 *** |
| COVID-19 time | |||
| Per-COVID-19 time | Referent | ||
| Pre-COVID-19 time | 0.05 | −0.01, 0.11 | 0.1 |
Residual standard error: 0.3322 on 458 degrees of freedom
Multiple R-squared: 0.7458, Adjusted R-squared: 0.7381
F-statistic: 96 on 14 and 458 DF, p-value: < 2.2e-16
aSignificant codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05