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. 2025 May 30;23:323. doi: 10.1186/s12916-025-04173-0

Table 2.

Clinical remission of the MN patients by intention-to-treat analysis

Cyclosporin + Sirolimus (n = 37) Cyclosporin monotherapy (n = 37) OR (95% CI)
Complete remission (CR), n (%)
 3 months 2/37 (5.4) 1/37 (2.7) 2.11 (0.18–23.72)
 6 months 2/36 (5.6) 2/36 (5.6) 1.00 (0.13–7.51)
 12 months 5/36 (13.9) 5/36 (13.9) 1.00 (0.26–3.80)
Partial remission (PR), n (%)
 3 months 14/37 (37.8) 17/37 (45.9) 0.72 (0.28–1.81)
 6 months 25/36 (69.4) 24/36 (66.7) 1.13 (0.42–3.06)
 12 months 21/36 (58.3) 19/36 (52.8) 1.25 (0.49–3.18)
Composite remission (CR + PR), n (%)
 3 months 16/37 (43.2) 18/37 (48.6) 0.80 (0.32–2.01)
 6 months 27/36 (75.0) 26/36 (72.2) 1.15 (0.40–3.30)
 12 months 26/36 (72.2) 24/36 (66.7) 1.30 (0.48–3.56)

The intention-to-treat population included all the patients who underwent randomization and received treatments. The primary outcome was clinical remission (CR + PR) at 12 months