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. 2025 May 30;18:196. doi: 10.1186/s13071-025-06832-w

Table 3.

Diagnostic performance values of serological testing compared with the reference standard test (UGS-positive results confirmed by real-time PCR and/or microscopy)

Reference standard test UGS confirmed by real-time PCR and/or microscopy
 +  −  Total Sensitivity (95% CI) Specificity (95% CI) PPV (95% CI) NPV (95% CI) Cohen’s kappa coefficient (95% CI)
Diagnostic test serology  +  24 158 182 88.9 (69.70- 97.09) 68.5 (64.23- 72.53) 13.2 (8.80- 19.18) 99.1 (97.28- 99.78) 0.16 (0.09- 0.22)
−  3 344 347
Total 27 502 529

95% CI: 95% confidence interval; PPV: positive predictive value; NPV: negative predictive value; UGS: urogenital schistosomiasis