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. 2025 May 30;25:2004. doi: 10.1186/s12889-025-23078-4

Table 2.

Single-metal regression models for the associations of urinary metals and SBP

Metals βa (95%CI) Quartiles of whole urine metals (μg/g creatinine)
Q1 Q2 Q3 Q4 P-trend
Al 0.002 (−0.007,0.011) Ref 0.031 (−0.002,0.063) 0.011 (−0.021,0.044) 0.014 (−0.018,0.047) 0.217
Ti −0.005 (−0.015,0.005) Ref 0.028 (−0.004,0.060) −0.000 (−0.033,0.032) −0.001 (−0.034,0.031) 0.441
V 0.009 (−0.005,0.022) Ref 0.000 (−0.032,0.033) 0.024 (−0.009,0.056) 0.012 (−0.020,0.045) 0.224
Cr 0.007 (−0.005,0.018) Ref 0.025 (−0.007,0.058) 0.019 (−0.013,0.052) 0.011 (−0.022,0.043) 0.568
Fe 0.006 (0.001,0.012)* Ref 0.036 (0.004,0.068)* 0.024 (−0.009,0.056) 0.037 (0.004,0.070)* 0.008
Mn 0.006 (0.001,0.012)* Ref 0.029 (−0.003,0.061) 0.038 (0.006,0.070)* 0.011 (−0.021,0.043) 0.515
Co 0.003 (−0.002,0.007) Ref 0.012 (−0.020,0.045) 0.015 (−0.017,0.048) 0.016 (−0.017,0.049) 0.099
Ni 0.006 (−0.001,0.012) Ref 0.020 (−0.012,0.053) 0.004 (−0.029,0.037) 0.022 (−0.010,0.055) 0.092
Cu 0.004 (−0.006,0.014) Ref −0.001 (−0.034,0.031) 0.004 (−0.029,0.037) 0.009 (−0.024,0.041) 0.543
As −0.004 (−0.021,0.012) Ref −0.001 (−0.033,0.032) 0.015 (−0.017,0.048) −0.005 (−0.037,0.027) 0.715
Zn −0.001 (−0.006,0.005) Ref 0.013 (−0.019,0.045) −0.000 (−0.032,0.032) −0.006 (−0.039,0.026) 0.751
Se 0.008 (−0.008,0.023) Ref 0.015 (−0.017,0.048) −0.001 (−0.034,0.031) 0.005 (−0.028,0.038) 0.676
Sr −0.001 (−0.004,0.003) Ref 0.014 (−0.018,0.046) 0.004 (−0.028,0.037) 0.009 (−0.023,0.041) 0.754
Mo −0.001 (−0.013,0.011) Ref 0.037 (0.005,0.069)* 0.008 (−0.024,0.041) −0.006 (−0.038,0.027) 0.171
Ag 0.001 (−0.002,0.003) Ref −0.017 (−0.049,0.015) 0.030 (−0.002,0.062) 0.008 (−0.024,0.040) 0.072
Cd 0.005 (−0.004,0.015) Ref 0.026 (−0.006,0.058) 0.013 (−0.019,0.046) 0.021 (−0.012,0.053) 0.196
Sb 0.003 (−0.001,0.006) Ref −0.003 (−0.036,0.029) 0.026 (−0.006,0.059) 0.015 (−0.018,0.047) 0.054
Tl 0.005 (−0.003,0.013) Ref −0.009 (−0.041,0.024) 0.017 (−0.015,0.050) 0.007 (−0.026,0.039) 0.075
Pb 0.001 (−0.002,0.004) Ref 0.003 (−0.029,0.036) 0.011 (−0.022,0.044) 0.015 (−0.018,0.047) 0.048

Al aluminium, Ti titanium, V vanadium, Cr chromium, Mn manganese, Fe iron, Co cobalt, Ni nickel, Cu copper, Zn zinc, As arsenic, Se selenium, Sr strontium, Mo molybdenum, Ag silver, Cd cadmium, Sb antimony, Ba barium, Tl thallium, Pb lead. All models had adjustments for age, sex, BMI, smoke, drink, education, family income, occupation

amultivariate linear regression, urinary metal and systolic blood pressure were ln-transformed. *p < 0.05