Table 2.

Effects of AE on fasting blood glucose (FBG) and serum insulin of T2DM after 28 days of treatment

Group	FBG after STZ induction (mmol/L)	FBG after 28 days (mmol/L)	Mean decrease in FBG	Percentage decrease in FBG (%)	Insulin Concentration (pg/mL)
NC	5.42 ± 0.21#	5.02 ± 0.15#	0.4 ± 0.24	6.58 ± 4.93	358.06 ± 9.47#
DC	19.48 ± 4.94*	20.05 ± 3.33*	-0.57 ± 2.98	-26.95 ± 25.56	167.55 ± 24.14*
PHZ	17.15 ± 2.17*	12.28 ± 2.95	4.87 ± 1.23	32.64 ± 10.25	287.81 ± 18.68#
AE250	13.84 ± 2.06	11.63 ± 2.76	4.15 ± 2.51	21.12 ± 21.39	310.66 ± 25.84#
AE500	19.92 ± 2.12*	14.48 ± 3.03	5.44 ± 3.60*	17.77 ± 26.19	258.85 ± 37.00*
AE1000	20.85 ± 3.63*	11.38 ± 1.78#	9.47 ± 4.15*	34.26 ± 16.56#	330.32 ± 19.59#

NC represents normal control rats, while PHZ refers to the group treated with 60 mg/kg B.W. phlorizin. AE250, AE500, and AE1000 indicate rats treated with AE at doses of 250 mg/kg B.W., 500 mg/kg B.W., and 1000 mg/kg B.W., respectively. Data are expressed as mean ± SEM (n = 6). *P < 0.05 compared to NC; #P < 0.05 compared to DC, as analyzed using one-way ANOVA with Dunnett-Tukey’s post hoc test