Table 2.
Characteristics of patients with radiographic axial spondylarthritis with and without bDMARDs
|
r-axSpA, without-bDMARDs, n = 15 |
r-axSpA, with bDMARDs, n = 13 | P value | |
|---|---|---|---|
| Age (year) | 64 [59–73] | 64 [51–68] | p = 0.17 |
|
Male number and age (year) Female number and age (year) |
10 (67%) 61 [59–65] 5 (33%) 71 [64–73] |
7 (54%) 55 [50–66] 6 (46%) 64 [53–70] |
p = 0.71 p = 0.98 p = 0.40 |
| Height (cm) | 174 [169–180] | 173 [168–179] | p = 0.70 |
| Weight (kg) | 86.5 [71.5–92.8] | 80.0 [71.0-85.2] | p = 0.39 |
| Symptom duration (year) | 33 [25–44] | 29 [27–37] | p = 0.56 |
| HLA-B27+ | 12 (80%) | 11 (85%) | p = 1.0 |
| NSAID | 5 (33%) | 3 (23%) | p = 1.0 |
| cDMARDS | 0 (0%) | 4 (31%) | p = 0.02 |
| ASDAS, score | 2.7 [1.52–2.64] | 1.68 [1.20–2.62] | p = 0.50 |
| CRP (mg/L) | 2.00 [2.00-5.80] | 2.60 [2.00-3.50] | p = 0.88 |
| ESR (mm/h | 12.5 [5.3–17.0] | 10.0 [7.0–30.0] | p = 0.64 |
| Hb (g/L) | 148 [142–158] | 145 [138–146] | p = 0.08 |
| WBC (109/L) | 6.3 [5.6–8.3] | 5.6 [5.4–5.9] | p = 0.07 |
| PLT (109/L) | 246 [232–267] | 250 [238–304] | p = 0.37 |
| ALT (µkat/L) | 0.41 [0.33–0.54] | 0.41 [0.36–0.48] | p = 0.95 |
| Creatinine (µmol/L) | 85 [76–98] | 75 [68–78] | p = 0.18 |
Values are stated as medians with 25th to 75th percentile or numbers with percentages. The Mann-Whitney U-test was used to compare patients with radiographic axial spondyloarthritis with and without biological disease-modifying antirheumatic drugs. r-axSpA; radiographic axial spondylarthritis, bDMARDS; biological disease-modifying antirheumatic drugs, HLA-B27; Human leukocyte antigen B27, NSAID; non-steroidal anti-inflammatory drug, cDMARDS; conventional disease-modifying antirheumatic drugs, ASDAS; Ankylosing Spondylitis Disease Activity Score, CRP; C-reactive protein, ESR; Erythrocyte Sedimentation Rate, Hb: Hemoglobin, WBC; White Blood Cell Count, PLT; Platelet Count, ALT; Alanine Aminotransferase