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. 2025 May 29;26:267. doi: 10.1186/s12882-024-03928-w

Table 2.

Comparison of differences in systolic blood pressure, diastolic blood pressure, and mean arterial pressure among patients before, during, and after dialysis at each time point

Index Number of cases T1(n = 54) T2(n = 54) T3(n = 54) T4(n = 54) T5(n = 54) T6(n = 54) F p
SBP before dialysis 54 143.02 ± 17.47 143.88 ± 15.17 f 143.28 ± 21.57 141.64 ± 17.09 139.65 ± 15.14 137.60 ± 14.69 b 2.293 0.046*
DBP before dialysis 54 76.11 ± 9.38 75.67 ± 9.36 76.25 ± 9.20 75.58 ± 8.68 75.34 ± 8.87 75.00 ± 8.08 0.371 0.869
MAP before dialysis 54 98.41 ± 10.48 98.40 ± 9.02 98.60 ± 10.67 97.60 ± 9.35 96.78 ± 9.01 95.87 ± 8.18 1.444 0.209
Mean SBP during dialysis 54 140.44 ± 15.98 141.04 ± 13.86 f 141.42 ± 17.33 f 138.71 ± 15.16 136.38 ± 14.41 134.81 ± 13.07 bc 4.645 0.000**
Mean DBP during dialysis 54 74.25 ± 8.13 73.97 ± 8.23 74.35 ± 7.89 71.71 ± 7.11 73.95 ± 7.21 73.29 ± 6.64 2.553 0.028*
Mean MAP during dialysis 54 96.31 ± 9.61 96.33 ± 8.21 96.71 ± 9.23 94.04 ± 7.94 94.76 ± 8.25 93.80 ± 7.46 2.907 0.014
After dialysis SBP 54 140.59 ± 16.08 141.82 ± 15.68 141.33 ± 16.64 139.42 ± 16.26 139.02 ± 14.66 137.79 ± 13.32 1.501 0.190
After dialysis DBP 54 73.46 ± 8.33 73.18 ± 8.49 72.49 ± 8.11 73.63 ± 7.93 73.97 ± 7.36 71.69 ± 7.02 1.269 0.277
After dialysis MAP 54 95.83 ± 9.83 96.06 ± 8.70 95.43 ± 8.99 95.56 ± 9.28 95.66 ± 8.16 93.73 ± 7.76 1.152 0.333

* p < 0.05 ** p < 0.01, T1: The sixth months before switching to roxadustat, T2: The third months before switching to roxadustat, T3: The first months before switching to roxadustat, T4: Switch to roxadustat for the first month, T5: Switch to roxadustat for the third month, T6: Switch to roxadustat for the sixth month. Compared to T1, a: P<0.05,A: P<0.001;Compared to T2, b:P<0.05,B: P<0.001; Compared to T3, c:P<0.05,C: P<0.001; Compared to T4, d:P<0.05,D: P<0.001; Compared to T5, e:P<0.05,E: P<0.001; Compared to T6, f:P<0.05,F: P<0.001 All experiments were repeated at least three times, and the average was selected as the observed data