Table 2.
Comparison of differences in systolic blood pressure, diastolic blood pressure, and mean arterial pressure among patients before, during, and after dialysis at each time point
| Index | Number of cases | T1(n = 54) | T2(n = 54) | T3(n = 54) | T4(n = 54) | T5(n = 54) | T6(n = 54) | F | p |
|---|---|---|---|---|---|---|---|---|---|
| SBP before dialysis | 54 | 143.02 ± 17.47 | 143.88 ± 15.17 f | 143.28 ± 21.57 | 141.64 ± 17.09 | 139.65 ± 15.14 | 137.60 ± 14.69 b | 2.293 | 0.046* |
| DBP before dialysis | 54 | 76.11 ± 9.38 | 75.67 ± 9.36 | 76.25 ± 9.20 | 75.58 ± 8.68 | 75.34 ± 8.87 | 75.00 ± 8.08 | 0.371 | 0.869 |
| MAP before dialysis | 54 | 98.41 ± 10.48 | 98.40 ± 9.02 | 98.60 ± 10.67 | 97.60 ± 9.35 | 96.78 ± 9.01 | 95.87 ± 8.18 | 1.444 | 0.209 |
| Mean SBP during dialysis | 54 | 140.44 ± 15.98 | 141.04 ± 13.86 f | 141.42 ± 17.33 f | 138.71 ± 15.16 | 136.38 ± 14.41 | 134.81 ± 13.07 bc | 4.645 | 0.000** |
| Mean DBP during dialysis | 54 | 74.25 ± 8.13 | 73.97 ± 8.23 | 74.35 ± 7.89 | 71.71 ± 7.11 | 73.95 ± 7.21 | 73.29 ± 6.64 | 2.553 | 0.028* |
| Mean MAP during dialysis | 54 | 96.31 ± 9.61 | 96.33 ± 8.21 | 96.71 ± 9.23 | 94.04 ± 7.94 | 94.76 ± 8.25 | 93.80 ± 7.46 | 2.907 | 0.014 |
| After dialysis SBP | 54 | 140.59 ± 16.08 | 141.82 ± 15.68 | 141.33 ± 16.64 | 139.42 ± 16.26 | 139.02 ± 14.66 | 137.79 ± 13.32 | 1.501 | 0.190 |
| After dialysis DBP | 54 | 73.46 ± 8.33 | 73.18 ± 8.49 | 72.49 ± 8.11 | 73.63 ± 7.93 | 73.97 ± 7.36 | 71.69 ± 7.02 | 1.269 | 0.277 |
| After dialysis MAP | 54 | 95.83 ± 9.83 | 96.06 ± 8.70 | 95.43 ± 8.99 | 95.56 ± 9.28 | 95.66 ± 8.16 | 93.73 ± 7.76 | 1.152 | 0.333 |
* p < 0.05 ** p < 0.01, T1: The sixth months before switching to roxadustat, T2: The third months before switching to roxadustat, T3: The first months before switching to roxadustat, T4: Switch to roxadustat for the first month, T5: Switch to roxadustat for the third month, T6: Switch to roxadustat for the sixth month. Compared to T1, a: P<0.05,A: P<0.001;Compared to T2, b:P<0.05,B: P<0.001; Compared to T3, c:P<0.05,C: P<0.001; Compared to T4, d:P<0.05,D: P<0.001; Compared to T5, e:P<0.05,E: P<0.001; Compared to T6, f:P<0.05,F: P<0.001 All experiments were repeated at least three times, and the average was selected as the observed data