TABLE 1.
Dataa |
P value for treeb:
|
|||
---|---|---|---|---|
pol
|
env gp41
|
|||
KH | SH | KH | SH | |
pol | Best ML tree | Best ML tree | 0.324 | 0.166 |
env gp41 | <0.001 | <0.001 | Best ML tree | Best ML tree |
polenv | 0.033 | 0.024 | Best ML tree | Best ML tree |
pol-RT | 0.822 | 0.388 | Best ML tree | Best ML tree |
polenv represents the concatenated pol and env gp41 alignment, and pol-RT represents the pol alignment after exclusion of the positions associated with drug resistance in the RT.
The results for the Kishino-Hasegawa (KH) and Shimodaira-Hasegawa (SH) tests are listed for the Hasegawa-Kishino-Yano model of evolution with gamma-distributed rate heterogeneity among sites; the tests for other models of evolution are consistent with these results (data not shown).