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Analysis of mutation spectra
| Mutational class | No. of mutants/total | Mutant frequencya (10−3) |
|---|---|---|
| +1 | 1/116 | 1.1 |
| −2 | 1/116 | 1.1 |
| −1 | 1/116 | 1.1 |
| G-to-T | 1/116 | 1.1 |
| Total | 4/116 | 4.4 |
Mutant frequency is in units of mutations/bp/cycle. The average number of relative light units for control experiments (virus replication in the presence of wild-type RT) was 6.1 × 102 + 35.
