Table 3.
The Causal Effect of Spermidine to Choline Ratio and Homostachydrine Levels on Pressure Ulcer Evaluated by IVW Method for MR Analysis
| Method | Nsnp | B | SE | p-value | Low_ci | Up_ci | OR | OR_lci95 | OR_uci95 | Heterogeneity_Q_p-val | Pleiotropy_p-val | PRESSO_p-val |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Spermidine to choline ratio | ||||||||||||
| MR Egger | 17 | 0.4655 | 0.2270 | 0.0583 | 0.0205 | 0.9105 | 1.5928 | 1.0207 | 2.4856 | 0.2640 | ||
| Weighted median | 17 | 0.2499 | 0.1555 | 0.1082 | −0.0550 | 0.5547 | 1.2838 | 0.9465 | 1.7414 | |||
| Inverse variance weighted | 17 | 0.3141 | 0.1185 | 0.0080 | 0.0818 | 0.5464 | 1.3690 | 1.0852 | 1.7270 | 0.2838 | 0.4445 | 0.3290 |
| Simple mode | 17 | 0.2455 | 0.2427 | 0.3269 | −0.2302 | 0.7212 | 1.2782 | 0.7943 | 2.0568 | |||
| Weighted mode | 17 | 0.2599 | 0.2091 | 0.2318 | −0.1499 | 0.6697 | 1.2968 | 0.8608 | 1.9536 | |||
| Homostachydrine levels | ||||||||||||
| MR Egger | 24 | −0.4332 | 0.1976 | 0.0392 | −0.8204 | −0.0460 | 0.6484 | 0.4402 | 0.9551 | 0.7542 | ||
| Weighted median | 24 | −0.3750 | 0.1367 | 0.0061 | −0.6430 | −0.1071 | 0.6873 | 0.5257 | 0.8985 | |||
| Inverse variance weighted | 24 | −0.2881 | 0.0964 | 0.0028 | −0.4771 | −0.0991 | 0.7497 | 0.6206 | 0.9056 | 0.7643 | 0.4092 | 0.7840 |
| Simple mode | 24 | −0.4860 | 0.2498 | 0.0640 | −0.9756 | 0.0035 | 0.6151 | 0.3770 | 1.0035 | |||
| Weighted mode | 24 | −0.4389 | 0.2197 | 0.0577 | −0.8695 | −0.0082 | 0.6448 | 0.4192 | 0.9918 | |||