Table 1. Databases applied search strategy, and numbers of retrieved studies .
| Database of published trials, dissertations and conference proceedings | Search strategy used | Hits |
| MEDLINE searched via PubMed searched on October 27, 2023th, via https://www.ncbi.nlm.nih.gov/ | #1 bioactive glass OR bioglass OR novamin OR 45S5 OR bioactive paste OR bioactive #2 orthodontic OR orthodontics OR brackets #3 #1 AND #2 |
449 |
| Web of Science Core Collection was searched via Web of Knowledge on November 1, 2023th, via apps.webofknowledge.com | #1 TS = (bioactive glass OR bioglass OR novamin OR 45S5 OR bioactive paste OR bioactive) #2 TS = (Orthodontics OR bracket) #3 #1 AND #2 |
72 |
| EMBASE searched via Ovid on November 1, 2023th, via https://www.embase.com/ | #1 ('novamin'/exp OR 'novamin' OR 45s5 OR 'bioactive glass'/exp OR 'bioactive glass' OR 'bioglass'/exp OR 'bioglass' OR 'bioglass 45s5'/exp OR 'bioglass 45s5' #2 'orthodontics'/exp OR orthodontics OR brackets #3 #1 AND #2 |
96 |
| Scopus searched via Scopus on October 28, 2023th, via https://www.scopus.com | TITLE-ABS-KEY (bioactive AND glass OR bioglass OR novamin OR 45s5 OR bioactive AND paste OR bioactive) AND TITLE-ABS-KEY (orthodontics OR brackets) | 84 |
| Cochrane Central Register of Controlled Trials searched via the Cochrane Library Searched on October 31, 2023th, via https://www.cochranelibrary.com/ | #1 bioactive glass 249 #2 bioglass 39 #3 bioactive paste 34 #4 orthodontic 5088 #5 (#1 OR #2 OR #3) AND #4 17 |
17 |
| Total | 718 |