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. 2025 May 15;12:1587713. doi: 10.3389/fcvm.2025.1587713

Table 1.

Description of primary and secondary endpoints.

Primary endpoint
Maximal value of troponin T (TnT) value during the first 24 h following myocardial reperfusion
Major secondary endpoint
1 Maximal value of creatinine kinase isoenzyme muscle-brain (CK-MB) during the first 24 h following myocardial reperfusion
Intra-operative related secondary endpoints
2 Time between the aortic cross-clamping and the complete cardiac arrest
3 Percentage of patients requiring catecholamines during aortic cross-clamping
4 Cumulative dose of catecholamines during aortic cross-clamping
5 Defibrillation rate after aorta unclamping and coronary reperfusion
ICU related secondary endpoints
6 Cumulative dose of catecholamines during the first 24 h following coronary reperfusion or until ICU discharge (if discharge occurs before 24 h), starting the calculation at arrival to ICU
7 Percentage of patients requiring the installation of an IABP during the first 24 h following coronary reperfusion or until ICU discharge (if discharge occurs before 24 h).
8 Duration of intubation
9 Duration of ICU stay
10 Mortality during the first 24 h following coronary reperfusion or until ICU discharge (if discharge occurs before 24 h)
11 Maximal ST elevation during the first 24 h following coronary reperfusion or until ICU discharge (if discharge occurs before 24 h)
Follow-up related secondary endpoints
12 Duration of hospitalization.
Safety endpoints
1 Serious and non-serious adverse events
2 Laboratory parameters