Table 1.
Comparison of part clinical and laboratory characteristics and outcomes based on the occurrence of anastomotic leakage. Qualitative data are presented as frequency (percentage), and Chi-square tests were applied to compare categorical data. Quantitative data are presented as mean (standard deviation), and independent sample t-tests were conducted for comparison. *denotes ≥ 0.01p < 0.05, ** denotes p < 0.01. AL: anastomotic leakage, RBC: red blood cell count, Hb: hemoglobin, GID: Gastrointestinal decompression drainage; POD: postoperative day, BMI: body mass index
| AL group (n = 55) | non-AL group n = 301) | P | ||
|---|---|---|---|---|
| Gender | Male | 48 (87.27%) | 241 (80.07%) | |
| Female | 7 (12.73%) | 60 (19.93%) | 0.280 | |
| Age, year | 65.44 (7.2) | 64.82 (7.96) | 0.640 | |
| BMI, kg/m2 | 23.41 (3.04) | 23.14 (3.51) | 0.340 | |
| lesion length, cm | 3.56 (1.4) | 3.15 (1.27) | 0.016* | |
| Esophageal Dilation | yes | 11 (20%) | 26 (8.64%) | |
| no | 44 (80%) | 275 (91.36%) | 0.020* | |
| Laparoscopic Surgery | yes | 46 (83.64%) | 178 (59.14%) | |
| no | 9 (16.36%) | 123 (40.86%) | 0.000** | |
| Surgery Type | Sweet | 9 (16.36%) | 124 (41.2%) | |
| Ivor-Lewis | 1 (1.82%) | 22 (7.31%) | ||
| McKeown | 45 (81.82%) | 155 (51.5%) | 0.000** | |
| no | 36 (65.45%) | 245 (81.4%) | 0.010* | |
| GID volume on POD 1, ml | 53.07 (70.87) | 85.68 (103.87) | 0.002** | |
| GID volume on POD 2, ml | 120.82 (183.09) | 196.71 (183.04) | 0.000** | |
| GID volume on POD 3, ml | 127.09 (170.68) | 202.61 (186.73) | 0.000** | |
| Preoperative Glutamate Dehydrogenase, U/L | 3.16 (2.49) | 4.11 (4.78) | 0.035* | |
| Preoperative RBC, ×10^12/L | 4.41 (0.44) | 4.21 (0.52) | 0.004** | |
| Preoperative Hb Concentration, g/L | 136.23 (14.86) | 130 (18.16) | 0.014* | |
| Preoperative Hematocrit, % | 41.75 (4.02) | 38.85 (5.14) | 0.000** | |
| Postoperative Magnesium, mmol/L | 0.83 (0.1) | 0.8 (0.11) | 0.044* | |
| Postoperative Fucosidase, U/L | 20.38 (4.6) | 18.28 (5.11) | 0.003** | |
| Postoperative Conjugated Bilirubin, µmol/L | 2.27 (1.33) | 1.88 (1.27) | 0.047* | |
| Postoperative RBC, ×10^12/L | 4.19 (0.53) | 4.04 (0.55) | 0.047* | |
| Postoperative Hb Concentration, g/L | 130.96 (17.3) | 125.61 (17.44) | 0.038* | |
| Postoperative Hematocrit, % | 39.4 (4.84) | 37.87 (4.86) | 0.033* | |
| Globulin difference, g/L | 2.84 (4.13) | 1.06 (4.49) | 0.008** | |
| Albumin Globulin Ratio difference, | 0.01 (0.28) | 0.14 (0.34) | 0.002** | |
| Prealbumin difference, mg/dL | 6.97 (4.96) | 5.34 (4.39) | 0.031* | |
| Fucosidase difference, U/L | -3.94 (4) | -2.51 (4.14) | 0.030* | |
| Magnesium difference, mmol/L | 0.06 (0.1) | 0.09 (0.12) | 0.027* | |