Table 5.
Mendelian randomization analysis identified several significant causal occupational exposure factors and maternal hypertensive disorders
| Outcomes | Exposure | Method | Nsnp | SE | Pval | OR | 95%CI |
|---|---|---|---|---|---|---|---|
| Pre-eclampsia or eclampsia | Workplace full of chemical or other fumes: Often | IVW | 20 | 0.95 | 0.007 | 13.08 | (2.04–83.65) |
| IVW | 20 | 1.80 | 0.165 | 13.5 | (0.40-457.9) | ||
| MR Egger | 20 | 1.30 | 0.105 | 8.21 | (0.64-104.42) | ||
| Weighted median | 20 | 2.01 | 0.368 | 6.39 | (0.12-330.39) | ||
| Simple mode | 20 | 1.70 | 0.273 | 6.77 | (0.24-188.26) | ||
| Pregnancy hypertension | Workplace full of chemical or other fumes: Often | IVW | 20 | 0.80 | 0.026 | 5.88 | (1.23–28.06) |
| MR Egger | 20 | 1.54 | 0.489 | 2.98 | (0.14–61.30) | ||
| Weighted median | 20 | 1.03 | 0.032 | 9.03 | (1.21–67.32) | ||
| Simple mode | 20 | 1.93 | 0.144 | 18.96 | (0.43-831.88) | ||
| Weighted mode | 20 | 1.70 | 0.135 | 14.25 | (0.51-401.56) |