Table 3.
Histopathological findings of NS lesions according to sex, age, and location.
| Histopathological findings | Gender | p value | Age | p value | Location | p value | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Female (n = 21) | Male (n = 39) | < 25 (n = 38) | ≥ 25 (n = 22) | Scalp (n = 25) | Face (n = 25) | |||||
| Orthokeratosis | Yes | 16 (76.2) | 29 (74.4) | 0.876∗ | 28 (73.7) | 17 (77.3) | 0.757∗ | 19 (76.0) | 18 (72.0) | 0.747∗ |
| No | 5 (23.8) | 10 (25.6) | 10 (26.3) | 5 (22.7) | 6 (24.0) | 7 (28.0) | ||||
|
| ||||||||||
| Focal parakeratosis | Yes | 3 (14.3) | 9 (23.1) | 0.513∗∗ | 6 (15.8) | 6 (27.3) | 0.327∗∗ | 8 (32.0) | 2 (8.0) | 0.034∗ |
| No | 18 (85.7) | 30 (76.9) | 32 (84.2) | 16 (72.7) | 17 (68.0) | 23 (92.0) | ||||
|
| ||||||||||
| Focal hypergranulosis | Yes | 6 (28.6) | 8 (20.5) | 0.532∗∗ | 8 (21.1) | 6 (27.3) | 0.583∗ | 6 (24.0) | 6 (24.0) | > 0.999∗ |
| No | 15 (71.4) | 31 (79.5) | 30 (78.9) | 16 (72.7) | 19 (76.0) | 19 (76.0) | ||||
|
| ||||||||||
| Acanthosis | Yes | 16 (76.2) | 33 (84.6) | 0.493∗∗ | 31 (81.6) | 18 (81.8) | > 0.999∗∗ | 24 (96.0) | 16 (64.0) | 0.005∗ |
| No | 5 (23.8) | 6 (15.4) | 7 (18.4) | 4 (18.2) | 1 (4.0) | 9 (36.0) | ||||
|
| ||||||||||
| Papillomatosis | Yes | 17 (81.0) | 34 (87.2) | 0.706∗∗ | 32 (84.2) | 19 (86.4) | > 0.999∗∗ | 23 (92.0) | 19 (76.0) | 0.247∗∗ |
| No | 4 (19.0) | 5 (12.8) | 6 (15.8) | 3 (13.6) | 2 (8.0) | 6 (24.0) | ||||
|
| ||||||||||
| Basal layer pigmentation | Yes | 5 (23.8) | 5 (12.8) | 0.298∗∗ | 6 (15.8) | 4 (18.2) | > 0.999∗∗ | 6 (24.0) | 3 (12.0) | 0.463∗∗ |
| No | 16 (76.2) | 34 (87.2) | 32 (84.2) | 18 (81.8) | 19 (76.0) | 22 (88.0) | ||||
|
| ||||||||||
| Sebaceous hyperplasia | Yes | 12 (57.1) | 25 (64.1) | 0.597∗ | 22 (57.9) | 15 (68.2) | 0.430∗ | 12 (48.0) | 19 (76.0) | 0.041∗ |
| No | 9 (42.9) | 14 (35.9) | 16 (42.1) | 7 (31.8) | 13 (52.0) | 6 (24.0) | ||||
|
| ||||||||||
| Terminal hair follicles | Yes | 10 (47.6) | 17 (43.6) | 0.765∗ | 17 (44.7) | 10 (45.5) | 0.957∗ | 15 (60.0) | 9 (36.0) | 0.089∗ |
| No | 11 (52.4) | 22 (56.4) | 21 (55.3) | 12 (54.5) | 10 (40.0) | 16 (64.0) | ||||
|
| ||||||||||
| Benign neoplasm | Yes | 3 (14.3) | 0 (0) | 0.039∗∗ | 1 (2.6) | 2 (9.1) | 0.548∗∗ | 1 (4.0) | 2 (8.0) | > 0.999∗∗ |
| No | 18 (85.7) | 39 (100.0) | 37 (97.4) | 20 (90.9) | 24 (96.0) | 23 (92.0) | ||||
|
| ||||||||||
| Malignant neoplasm | Yes | 4 (19.0) | 2 (5.1) | 0.171∗∗ | 0 (0) | 6 (27.3) | 0.001∗∗ | 5 (20.0) | 1 (4.0) | 0.189∗∗ |
| No | 17 (81.0) | 37 (94.9) | 38 (100.0) | 16 (72.7) | 20 (80.0) | 24 (96.0) | ||||
|
| ||||||||||
| Demodex infestation | Yes | 10 (47.6) | 24 (61.5) | 0.299∗ | 21 (55.3) | 13 (59.1) | 0.773∗ | 14 (56.0) | 16 (64.0) | 0.564∗ |
| No | 11 (52.4) | 15 (38.5) | 17 (44.7) | 9 (40.9) | 11 (44.0) | 9 (36.0) | ||||
|
| ||||||||||
| Apocrine glands dilatation | Yes | 5 (23.8) | 9 (23.1) | > 0.999∗∗ | 11 (28.9) | 3 (13.6) | 0.177∗ | 7 (28.0) | 5 (20.0) | 0.508∗ |
| No | 16 (76.2) | 90 (76.9) | 27 (71.1) | 19 (86.4) | 18 (72.0) | 20 (80.0) | ||||
Note: N: number.
∗ q square test; a p value of less than 0.05 was considered statistically significant.
∗∗Fisher's exact test.