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. 2025 Jun 3;18:23. doi: 10.1186/s13044-025-00239-6

Table 2.

Comparison of micronutrientstatus and T3 levels in adolescent Afghan refugees. Comparison was achieved by dividing participants into three equally-sized tertiles according to T3 levels

Characteristics T3
Overall Tertile 1 Tertile 2 Tertile 3 P-trend
Median (Q1, Q3) of T3 1.05 (0.93, 1.16) 1.42 (1.33, 1.51) 1.79 (1.67, 2.06)
All age groups
Ferritin (ng/mL) 39 (27, 61.4) 48.0 (29.5, 79.6) 35.0 (24.6, 49.0) 40.6 (26.54, 59.45) 0.09
Folate (ng/mL) 4.4 (3.4, 6.1) 4.6 (3.1, 6.6) 4.3 (3.6, 5.8) 4.2 (3.6, 6) 0.82
Vitamin B12 (pg/mL) 219 (157, 348) 228 (167, 392) 220.0 (155.0, 349.0) 205.0 (161.0, 300.0) 0.29
Vitamin D (ng/mL) 22.3 (16.2, 27.5) 20.4 (13.9, 25.1) 25.3 (19.3, 28.9) 21.5 (15.7, 26.9) 0.17
Zinc (µg/L) 787 (619, 932) 809 (637, 939) 784.5 (623.8, 934.4) 758.6 (593.7, 891.7) 0.33
Copper (µg/L) 951 (791, 1147) 936 (771, 1217) 970.2 (827.1, 1134.6) 951.4 (797.1, 1082.3) 0.56
Selenium (µg/L) 71.1 (50.5, 91.3) 72.4 (55.4, 93.3) 75.2 (50.5, 96.1) 62.9 (45.1, 84.2) 0.10
Age (10–14)
Ferritin (ng/mL) 37.7 (27.8, 51.6) 39.4 (29.5, 60.3) 35.5 (26.9, 44.7) 40.7 (27.2, 59.5) 0.95
Folate (ng/mL) 4.7 (3.6, 6.1) 5.3 (4, 6.8) 4.5 (3.625, 5.7) 4 (3.6, 5.7) 0.08
Vitamin B12 (pg/mL) 209 (155, 310) 209.5 (157, 337) 213.5 (155.5, 302.5) 205.0 (154.0, 287.0) 0.56
Vitamin D (ng/mL) 24.1 (7.3) 22.9 (6.9) 24.1 (7.5) 25.0 (7.5) 0.33
Zinc (µg/L) 789.6 (605.6, 934.4) 773.2 (576.6, 900.7) 798.4 (631.2, 933.7) 789.6 (642.6, 949.4) 0.46
Copper (µg/L) 992 (824.6, 1146.8) 933.3 (765.7, 1188.6) 1014.1 (837.4, 1146.4) 987.7 (824.6, 1118.3) 0.78
Selenium (µg/L) 72 (48.4, 91.4) 73.4 (49.3, 102.5) 70.5 (46.3, 95.5) 68.5 (54.2, 86.2) 0.48
Age (15–18)
Ferritin (ng/mL) 48.3 (23.5, 79.8) 66.1 (31.3, 105.4) 34.1 (17.5, 57.3) 35.2 (23.1, 56.5) 0.04
Folate (ng/mL) 4 (3.1, 6.3) 4 (2.85, 6.05) 4 (3, 6.2) 4.8 (3.6, 6.7) 0.20
Vitamin B12 (pg/mL) 244 (170, 400) 250.0 (174.5, 428.5) 250.0 (148.0, 443.0) 207.0 (175.0, 349.5) 0.59
Vitamin D (ng/mL) 17.3 (12, 25.1) 16.8 (12, 23.65) 24.4 (14.9, 30.4) 14.7 (11.35, 17.35) 0.91
Zinc (µg/L) 784.5 (621.4, 905.2) 838.3 (713.5, 969.1) 697.2 (623.8, 1011.0) 632.9 (539.5, 746.0) 0.004
Copper (µg/L) 926.1(731.2, 1107.3) 947.3 (773.6, 1235.0) 941.1 (761.1, 975.4) 817.1 (615.5, 991.4) 0.09
Selenium (µg/L) 70.6 (51.5, 89.5) 71.1 (55.6, 88.4) 85.9 (53.0, 100.2) 42.9 (37.7, 71.5) 0.08

Mean and range of T3 levels in each tertile were: Tertile 1 (mean = 2.0 µg/dL; range = 1.5–2.5 µg/dL) Tertile 2 (mean = 3.0 µg/dL; range = 2.6–3.5 µg/dL) and Tertile 3 (mean = 4.0 µg/dL, range of 3.6–4.5 µg/dL). Significant differences are indicated in bold. A P-trend value of < 0.05 indicates that the the observed trend is significant (increase or decrease of the micronutrient indicator across the T3 tertials) and was determined using the Jonckheere-Terpstra test