Table 1.

Work-up for radioembolization.

	Minimal work-up		Additional work-up
Clinical assessment	Patient level of functioning	ECOG performance score	Fibroscan/gastroscopy	Assess esophageal varices
	Signs of hepatic dysfunction	Child-Pugh or MELD score
	NET hormone-related symptoms	Assessment of clinical response
Blood work	Liver function	Bilirubin, ALP, AST, ALT, albumin	Hb, hematocrit, WBC, platelets	Assess anemia or bleeding disorders
	Kidney function	Creatinine, eGFR; for angiography
	Tumor markers	Assessment of biochemical response
	Coagulation assessment	E.g., prothrombin time or INR; for angiography
Imaging studies	GdMRI/contrast-enhanced CT	Assess intrahepatic tumor load	SSTR-PET-CT	Assess total body tumor load
	Early contrast-enhanced CT	Assess liver arterial vascularization	FDG-PET-CT	Assess tumor grade distinction and exclusion aggressive disease

Abbreviations: ECOG, Eastern Cooperative Oncology Group; NET, neuroendocrine tumor; ALP, alkaline phosphatase; AST, aspartate aminotransferase; ALT, alanine; eGFR, estimated glomerular filtration rate; CgA, chromogranin A; INR, international normalized ratio; GdMRI, gadolinium-enhanced magnetic resonance imaging; CT, computed tomography; Hb, hemoglobin; WBC, white blood count; SSTR, somatostatin receptor; PET, positron emission tomography; FDG, fluorodeoxyglucose.