Table 1.

Research initiatives of psychiatric genetic research in Latin American populations.

Initiative	Psychiatric Disorder(s)	Countries involved	Description	Reference	Website
Latin American Network for the Study of Early Psychosis (ANDES)	Schizophrenia	Argentina, Brazil, Bolivia, Chile, Colombia, and Mexico	Focused on genetic studies of early psychosis as well as clinical, cognitive, epidemiological, economic, and neuroimaging analyses.	145	https://www.cyted.org/andes
COllaborative Case-Control INitiativE in crack addiction (COCCaINE)	Substance use disorders	Brazil	Population-based genetic epidemiological study of cocaine use disorder in Brazil.		https://reporter.nih.gov/project-details/9709257
Comprehensive exploration of the CONNECTion between ADHD and educational attainment in contrasting environments (CONNECT- ADHD)	Attention deficit hyperactivity disorder	Brazil	A project within the NIMH-funded Ancestral Populations Network (APN) and the LAGCADHD working group.		https://www.nimh.nih.gov/about/organization/dnbbs/genomics-research-branch/ancestral-populations-network-apn
Eating Disorders Genetics Initiative - Mexico (EDGI-Mexico)	Eating disorders	Mexico	Focused on genetic studies of eating disorders in Mexico.	143,146	https://edgi.org/
Genetic Architecture of Early-Onset Psychosis in Mexicans (EPIMEX)	Psychosis	Mexico and USA	To investigate the genetic architecture of early onset psychosis in a pediatric cohort from Mexico.	128	https://www.epimex.net/ https://www.nimh.nih.gov/about/organization/dnbbs/genomics-research-branch/ancestral-populations-network-apn
Genomics of Autism in Latinx Ancestries (GALA)	Autism spectrum disorder	Brazil, Colombia, Peru, and USA	A collaborative network between Brazil, Colombia, Peru, and the United States focused on the genomics of autism.	128	https://www.nimh.nih.gov/about/organization/dnbbs/genomics-research-branch/ancestral-populations-network-apn
Latin American Genomics Consortium (LAGC)	All psychiatric disorders	Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Mexico, Peru, Puerto Rico, USA, Canada, Spain, Australia	Established in 2019, the aim of the consortium is to advance psychiatric genomics research in Latin American populations.		https://www.latinamericangenomicsconsortium.org/
Trans-Ancestry Genomic Analysis of Obsessive-Compulsive Disorder (LATINO)	Obsessive compulsive disorder	Argentina, Bolivia, Brazil, Canada, Chile, Colombia, Ecuador, El Salvador, Honduras, Mexico, Paraguay, Peru, USA	An NIMH-funded effort to collect DNA and comprehensive phenotypic data from 5,000 Latin American OCD cases.	86,128	https://orit.research.bcm.edu/latinostudy/en
Neuropsychiatric Genetics of Psychosis in Mexican Populations (NeuroMEX)	Bipolar disorder, psychosis, schizophrenia	Mexico	Aims to recruit 4,000 psychosis cases and 4,000 controls from Mexico.	144,145	https://www.broadinstitute.org/stanley-global/neuromex
Paisa Project	Schizophrenia, bipolar disorder, major depressive disorder	Colombia	To establish a cohort of 8,000 mood or psychotic disorders cases and 2,000 healthy controls from the Paisa region in Colombia.	145,147
Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries (PUMAS)	Bipolar disorder, schizophrenia	Brazil, Colombia, Ethiopia, Kenya, Nigeria, Uganda, South Africa, and USA	To recruit 40,000 schizophrenia cases, 40,000 bipolar disorder cases, and 40,000 matched controls.	128	https://www.nimh.nih.gov/about/organization/dnbbs/genomics-research-branch/ancestral-populations-network-apn