Table 3.
(A) Nutritional intake during the first 4 weeks of life and (B) Spearman correlation for caloric and protein intake for first 4 weeks of life versus z-score for length at 4 weeks of life, 36 weeks PMA and at the time of MRI.
| A | ||||
|---|---|---|---|---|
| Characteristics* | Grade 1 BPD n=19 |
Grade 2 BPD n=32 |
Grade 3 BPD n=44 |
P values |
| Fluid, week 1, ml/kg/day | 145 (16) | 145 (19) | 146 (20) | 0.72 |
| Fluid, week 2, ml/kg/day | 162 (16) | 153 (12) | 154 (18) | 0.021 |
| Fluid, week 3, ml/kg/day | 157 (8) | 155 (15) | 152 (17) | 0.11 |
| Fluid, week 4, ml/kg/day | 152 (8) | 149 (11) | 152 (15) | 0.54 |
| Fluid, over 4 weeks of life, ml/kg/day | 154 (7) | 150 (10) | 151 (12) | 0.12 |
| Kcal/kg/d, week 1 | 74 (10) | 72 (10) | 71 (11) | 0.66 |
| Kcal/kg/d, week 2 | 109 (20) | 101 (17) | 101 (16) | 0.20 |
| Kcal/kg/d, week 3 | 121 (14) | 105 (15) | 104 (19) | 0.0041 |
| Kcal/kg/d, week 4 | 120 (13) | 113 (12) | 109 (19) | 0.072 |
| Kcal/kg/d, over 4 weeks | 106 (11) | 98 (10) | 96 (12) | 0.031 |
| Protein/kg/day, week 1 | 3.43 (0.41) | 3.45 (0.35) | 3.42 (0.42) | 0.98 |
| Protein/kg/day, week 2 | 4.23 (0.40) | 3.92 (0.48) | 3.98 (0.50) | 0.062 |
| Protein/kg/day, week 3 | 4.22 (0.59) | 3.72 (0.51) | 3.78 (0.57) | 0.021 |
| Protein/kg/day, week 4 | 4.06 (0.60) | 3.92 (0.43) | 3.97 (0.62) | 0.72 |
| Protein/kg/day, over 4 weeks | 3.99 (0.32) | 3.75 (0.28) | 3.79 (0.38) | 0.051 |
| B | z-score for length | ||
|---|---|---|---|
| 4 weeks of life | 36 weeks PMA | Time of MRI | |
| Caloric intake, first 4 weeks of life, kcal/kg/day | R=0.21, p=0.04 | R=0.25, p=0.02 | R=0.41, p<0.001 |
| Protein intake, first 4 weeks of life, g/kg/day | R=0.24, p=0.02 | R=0.12, p=0.25 | R=0.21, p=0.04 |
*
all data presented as mean (SD); week 1 = day of life 1-7, week 2 = day 8-14, week 3 = d 15-21, week 4 = day 22-28
1 -
one-way ANOVA test is significant; post hoc test showed significant difference between grades 1 and 2, and grades 1 and 3 disease but not significant between grades 2 and 3.
2 -
one-way ANOVA test is marginally significant; post hoc test showed significant difference between grades 1 and 3 disease but not significant between grades 1 and 2, and grades 2 and 3.