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. 2025 May 1;22(6):3351–3365. doi: 10.1021/acs.molpharmaceut.5c00254

2. Physicochemical characterizationSize, Polydispersity Index (PDI), Zeta Potential (ZP), Nanoparticle Concentration (NC), and BVCS75 Encapsulation Efficiency (%ee)of the Formulations with Bupivacaine (NLC-L-BVC and NLC-BVC) and with Lavender Oil Alone (NLC-L).

Formulation Size (nm) PDI ZP (mV) NC (x 1013/mL) %EE
NLC-L 195.4 ± 1.8 0.138 ± 0.03 -26.8 ± 0.8 3.1 ± 0.2 -
NLC-L-BVC 200.5 ± 2.4 0.140 ± 0.02 -34.0 ± 0.6 3.8 ± 0.3 89.0 ± 2.3
NLC-BVC 165.9 ± 1.5 0.123 ± 0.05 -37.0 ± 1.1 8.8 ± 0.1 91.0 ± 3.4
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See ref .