TABLE 3.
Modified Matutes/Moreau and adapted Matutes scores for the diagnosis of chronic lymphocytic leukemia at Universitas Academic Hospital, Bloemfontein, South Africa, January 2022 to March 2023.
Marker | Score points† |
|
---|---|---|
1 | 0 | |
Modified Matutes/Moreau score | ||
sIg | Dim | Bright |
CD5 | Positive | Negative |
CD23 | Positive | Negative |
FMC7/CD20 | Negative | Positive |
CD79b | Dim | Bright |
Adapted Matutes score | ||
sIg | Dim | Bright |
CD5 | Positive | Negative |
CD23 | Positive | Negative |
CD200 | Positive | Negative |
Source: Adapted from Moreau EJ et al.6 and Jalal SD.10 Please see the reference list of this article, Grobler SM, Van Marle A-C. Effects of sample age and storage temperature on the flow cytometric diagnosis of chronic lymphocytic leukaemia in South Africa. Afr J Lab Med. 2025;14(1), a2688. https://doi.org/10.4102/ajlm.v14i1.2688, for more information
sIg, surface immunoglobulin; CD, cluster of differentiation; FMC, epitope on CD20.
, Score > 3: strong correlation with a diagnosis of CLL; score = 3: atypical CLL; score < 3 unlikely for chronic lymphocytic leukaemia and more likely for other B-cell lymphoproliferative disorders.