Skip to main content
. 2025 Feb 17;48(6):1827–1838. doi: 10.1038/s41440-025-02152-9

Table 2.

Effects of the patient care team for hypertension on office systolic blood pressure in subgroups

Subgroups Trials Mean difference (mmHg) Heterogeneity (%) Test for overall effect P-value for heterogeneity
N Mean (95% CI) I2 P-value Z P-value P-value
Intervention 0.46
 Pharmacist-led 22 −5.74 (−7.10, −4.38) 74 <0.001 8.27 <0.001
 Nurse-led 16 −5.79 (−7.69, −3.88) 74 <0.001 5.96 <0.001
 Physician-led 6 −4.07 (−7.31, −0.83) 76 <0.001 2.46 <0.001
 CHW-led 6 −8.02 (−16.10, 0.07) 99 <0.001 1.94 0.05
 Others 7 −8.03 (−10.95, −5.10) 42 0.11 5.37 <0.001
Follow-up periods 0.37
 ≤6 months 33 −6.15 (−7.20, −5.11) 59 <0.001 11.55 <0.001
 >6 to ≤12 months 16 −4.77 (−6.77, −2.77) 84 <0.001 4.68 <0.001
 >12 months 8 −8.51 (−15.55, −1.48) 99 <0.001 2.37 0.02
Mean age 0.89
 <65 years 47 −6.27 (−7.85, −4.69) 95 <0.001 7.79 <0.001
 ≥65 years 10 −6.53 (−9.94, −3.11) 81 <0.001 3.75 <0.001
Countries/regions 0.59
 United States 30 −6.24 (−7.55, −4.93) 68 <0.001 9.32 <0.001
 China/Hong Kong 10 −7.36 (−14.08, −0.65) 99 <0.001 2.15 0.03
 Other countries/regions 17 −5.34 (−6.72, −3.95) 72 <0.001 7.56 <0.001

CHW community health worker, CI confidence interval, HT hypertension, N number