Table 3.
Ongoing Trials in LS-SCLC Patients
| Identifier | Patients | Phase | Intervention Arm | Control Arm | Primary Endpoint |
|---|---|---|---|---|---|
| NCT05496166 | LS-SCLC N=348 |
III | Adebrelimab + chemotherapy → surgery→ Adebrelimab | Adebrelimab + chemotherapy→radiotherapy → Adebrelimab | PFS |
| NCT06483282 | LS-SCLC N=38 |
II | Adebrelimab + Apatinib + Chemotherapy → surgery → Adebrelimab + Apatinib ± radiotherapy |
- | EFS |
| NCT06527898 | LS-SCLC N=45 |
I/II | Chemotherapy + concurrent hypofractionated radiotherapy → Adebrelimab + chemotherapy → Adebrelimab | - | PFS |
| ChiCTR2400082364 | LS-SCLC N=36 |
II | Hyperfractionated radiotherapy + chemotherapy → adebrelimab maintenance | - | Safety PFS |
| ChiCTR2500095305 | LS-SCLC N=58 |
IV | Adebrelimab + chemotherapy → Adebrelimab + chemotherapy + radiotherapy | - | PFS |
| ChiCTR2400086355 | LS-SCLC N=38 |
- | Adebrelimab + chemotherapy → chemotherapy + radiotherapy → Adebrelimab | - | PFS |
Abbreviations: LS-SCLC, limited-stage small cell lung cancer; PFS, progression-free survival; EFS, event-free survival.